Patents Assigned to PROSENTA TECHNOLOGIES B.V.
  • Publication number: 20100184833
    Abstract: The current invention provides for methods and medicaments that apply oligonucleotide molecules complementary only to a repetitive sequence in a human gene transcript, for the manufacture of a medicament for the diagnosis, treatment or prevention of a cis-element repeat instability associated genetic disorders in humans. The invention hence provides a method of treatment for cis-element repeat instability associated genetic disorders. The invention also pertains to modified oligonucleotides which can be applied in method of the invention to prevent the accumulation and/or translation of repeat expanded transcripts in cells.
    Type: Application
    Filed: August 10, 2007
    Publication date: July 22, 2010
    Applicant: PROSENTA TECHNOLOGIES B.V.
    Inventors: Josephus Johannes De Kimpe, Gerard Johannes Platenburg, Derick Gert Wansink