Patents Assigned to PROTAGEN AKTIENGESELLSCHAFT
  • Method for diagnosis of high-affinity binders and marker sequences
    Patent number: 10060911
    Abstract: The present invention relates to a novel method for diagnosing high-affinity binders, in particular antibodies or autoantibodies, and the identification, characterization and selection of marker sequences and diagnostic use thereof, in particular in the form of a panel. The invention also relates to a singleplex assay in which the discovered selection of marker sequences is used in the form of a panel and high-affinity binders are detected using a single signal.
    Type: Grant
    Filed: August 18, 2012
    Date of Patent: August 28, 2018
    Assignee: Protagen Aktiengesellschaft
    Inventors: Stefan Müllner, Peter Schulz-Knappe, Angelika Lueking, Heike Göhler, Jessica Schwermann
  • MARKER SEQUENCES FOR DIAGNOSING PROSTATE CANCER, AND USE THEREOF
    Publication number: 20140179557
    Abstract: The present invention relates to novel marker sequences for prostate carcinoma while excluding inflammatory prostate diseases or diabetes or polymorbidity and relates to their diagnostic use including a method for screening potential active substances for such prostate diseases by means of these marker sequences. The invention furthermore relates to a diagnostic device including such marker sequences for prostate carcinoma, in particular a protein biochip and its use.
    Type: Application
    Filed: February 24, 2014
    Publication date: June 26, 2014
    Applicant: PROTAGEN AKTIENGESELLSCHAFT
    Inventors: ANGELIKA LUEKING, AXEL KOWALD, HELMUT KLOCKER
  • MARKER SEQUENCES FOR SYSTEMIC LUPUS ERYTHEMATOSUS AND THE USE THEREOF
    Publication number: 20130303395
    Abstract: The invention relates to novel marker sequences for systemic lupus erythematosus and to the use thereof in diagnosis as well as to a method for screening potential active ingredients for systemic lupus erythematosus diseases using said marker sequences. The invention further relates to a diagnostic device containing such marker sequences for systemic lupus erythematosus, especially to a protein biochip and the use thereof.
    Type: Application
    Filed: October 12, 2011
    Publication date: November 14, 2013
    Applicant: PROTAGEN AKTIENGESELLSCHAFT
    Inventors: Angelika Lueking, Axel Kowald, Stefan Müllner, Christian Scheer, Matthias Schneider
  • Marker Sequences for Inflammatory Prostate Diseases, Prostate Carconoma and Their Use
    Publication number: 20130217591
    Abstract: The present invention relates to novel marker sequences for inflammatory prostate diseases, prostate carcinoma and the diagnostic use thereof together with a method for screening of potential active substances for inflammatory prostate diseases, prostate carcinoma by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for inflammatory prostate diseases, prostate carcinoma, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: April 10, 2013
    Publication date: August 22, 2013
    Applicant: PROTAGEN AKTIENGESELLSCHAFT
    Inventors: HELMUT E. MEYER, ANGELIKA LUEKING, JENS BEATOR, AXEL KOWALD, GEORG BARTSCH, HELMUT KLOCKER
  • BIOMARKERS FOR ALZHEIMER'S DISEASE
    Publication number: 20130029864
    Abstract: The invention relates to novel marker sequences for Alzheimer's disease, in particular Alzheimer's dementia, and their diagnostic use including a screening method in order to identify potential drugs for the treatment/prophylaxis of Alzheimer's disease by means of the said novel marker sequences. Moreover, the invention relates to a diagnostic device comprising said novel marker sequences for diagnosing Alzheimer's disease, particularly a protein array (chip) and its use hereto.
    Type: Application
    Filed: October 1, 2010
    Publication date: January 31, 2013
    Applicant: PROTAGEN Aktiengesellschaft
    Inventors: Angelika Lueking, Stefan Müllner, Charlotte Teunissen, Jens Wiltfang
  • Marker Sequences for Pancreatic Cancer Diseases, Pancreatic Carcinoma and Use Thereof
    Publication number: 20120264634
    Abstract: The present invention relates to novel marker sequences for pancreatic cancer diseases, pancreatic carcinoma and the diagnostic use thereof together with a method for screening of potential active substances for pancreatic cancer diseases, pancreatic carcinoma by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for pancreatic cancer diseases, pancreatic carcinoma, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: September 29, 2010
    Publication date: October 18, 2012
    Applicant: PROTAGEN Aktiengesellschaft
    Inventors: Peter Amersdorfer, Annabel Höpfner, Angelika Lueking
  • MARKER SEQUENCES FOR INFLAMMATORY PROSTATE DISEASES, PROSTATE CARCINOMA AND THEIR USE
    Publication number: 20110275528
    Abstract: The present invention relates to novel marker sequences for inflammatory prostate diseases, prostate carcinoma and the diagnostic use thereof together with a method for screening of potential active substances for inflammatory prostate diseases, prostate carcinoma by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for inflammatory prostate diseases, prostate carcinoma, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: July 6, 2009
    Publication date: November 10, 2011
    Applicant: PROTAGEN Aktiengesellschaft
    Inventors: Helmut E. Meyer, Angelika Leukling, Jens Beator, Axel Kowald, Georg Bartsch, Helmut Klocker
  • MARKER SEQUENCE FOR NEURODEGENERATIVE DISEASES AND THE USE THEREOF
    Publication number: 20110184375
    Abstract: The present invention relates to new marker sequences for neurodegenerative diseases and the diagnostic use thereof together with a method for screening of potential active substances for neurodegenerative diseases by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for neurodegenerative diseases, in particular a protein biochip and the use thereof.
    Type: Application
    Filed: December 22, 2008
    Publication date: July 28, 2011
    Applicant: Protagen Aktiengesellschaft
    Inventors: Heike Göhler, Helmut E. Meyer, Katrin Marcus, Axel Kowald, Florian Tribl, Manfred Gerlach, Peter Riederer, Angelika Lüking, Christian Scheer, Jens Beator
  • PROTEIN BIOCHIP FOR THE DIFFERENTIAL SCREENING OF PROTEIN-PROTEIN INTERACTIONS
    Publication number: 20100331201
    Abstract: The present invention relates to a system of protein binders containing at least one protein binder presented in at least one native form and at least one non-native form and its use including a method for discrimination and/or differential screening of suitable protein binders in native and non-native form.
    Type: Application
    Filed: June 11, 2007
    Publication date: December 30, 2010
    Applicant: PROTAGEN Aktiengesellschaft
    Inventors: Stefan Müllner, Angelika Lüking, Verena Trappe
  • S-Nitrosothiols Containing Composition for the Treatment of Fatty Liver Diseases, Obesity and Other Diseases Associated with the Metabolic Syndrome and the Use of Such Compositions
    Publication number: 20100062059
    Abstract: The present invention refers to pharmaceutical compositions containing S-nitrosothiols as active principle. The referred compositions are intended for the treatment of the fatty liver disease and other diseases associated with the metabolic syndrome. The composition is administered either orally or rectally.
    Type: Application
    Filed: April 20, 2007
    Publication date: March 11, 2010
    Applicant: PROTAGEN AKTIENGESELLSCHAFT
    Inventor: Marcelo Ganzarolli De Oliveira