Abstract: The present invention relates to a biosensor for inspecting the susceptibility of a microorganism to an antibiotic, a fabrication method therefor, and a method for inspecting the susceptibility of a microorganism to an antibiotic by using same, wherein the biosensor comprises: a substrate including polyethylene terephthalate; and a sensor part formed on one surface or both surfaces of the substrate and comprising an electrode inclusive of a first electrode and a second electrode which interdigitate with each other.
Type:
Application
Filed:
December 17, 2021
Publication date:
February 8, 2024
Applicant:
PROTEOMETECH INC.
Inventors:
Kook Jin LIM, Han Seung JOO, Je Seung OH, Chang Su LIM
Abstract: The present invention relates to a chromatography strip for diagnosing pregnancy having multiple test lines, a pregnancy diagnosis kit having the chromatography strip, and a method for diagnosing pregnancy using the same. The present invention overcomes the problem of false negatives due to hCG variants such that pregnancy can be determined more accurately and conveniently by the naked eye. Furthermore, there is an effect of improving the concentration measurement range of hCG or a variant thereof by using a chromatography strip for diagnosing pregnancy which is constituted by multiple test lines and control lines.
Type:
Application
Filed:
July 10, 2019
Publication date:
May 12, 2022
Applicant:
ProteomeTech Inc.
Inventors:
Kook Jin LIM, Tae Hyong KIM, Dong Suk PARK, Dong Seob CHOI, Mi Jeoung KIM, Young Woo PARK
Abstract: The present invention relates to: a chromatographic strip comprising a plurality of test lines for a competitive assay; a diagnostic kit comprising the chromatographic strip; and a method for qualitatively or quantitatively analyzing a target material within a specimen by using the same. By using the chromatographic strip of the present invention, qualitative analysis and highly reliable quantitative analysis can be rapidly and conveniently carried out with the naked eyes or a sensor even for a target material, which has one ligand binding position or is small. Furthermore, the present invention has an effect of improving the concentration measurement range of an analyte by the mutual supplementation of test lines and control lines.
Type:
Application
Filed:
September 7, 2018
Publication date:
June 3, 2021
Applicant:
ProteomeTech Inc.
Inventors:
Kook Jin LIM, Tae Hyoung KIM, Dong Suk PARK, Seok Kyo SHIN, Mi Jeoung KIM
Abstract: An apparatus for inspecting an antibiotic and a method for determining antibiotic sensitivity using the same is provided. The antibiotic susceptibility inspection time which has conventionally taken longer than 24 hours is shortened to about 2 hours or less, the efficacy of the target substance is monitored in real time, the identification of the microorganism, the kind of the antibiotic capable of treating the microorganism, and the minimum dosage thereof are quickly confirmed. Microbial infections requiring prompt diagnosis and treatment can be effectively treated.
Type:
Application
Filed:
October 12, 2020
Publication date:
May 13, 2021
Applicants:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, PROTEOMETECH INC.
Inventors:
Kyung Hwa YOO, Nal Ae HAN, Bong Jun KIM, Sun Mi LEE, Kook Jin LIM, Jeseung OH
Abstract: Provided are an autoantibody specifically binding to an exosomal protein EIF3A (Eukaryotic translation initiation factor 3 subunit A) or a fragment including an antigen-binding site (paratope) thereof, a hybridoma cell line producing the autoantibody, a polypeptide having an amino acid sequence of an antigenic determinant (epitope) specifically binding to the autoantibody, a composition for diagnosing liver cancer including an agent measuring an expression level of the autoantibody or the fragment including the antigen-binding site thereof, a kit for diagnosing liver cancer including the composition, and a method of providing information for diagnosis of liver cancer by using the composition. Further, provided is a method of screening for a therapeutic agent for liver cancer by using an expression level of the autoantibody.
Type:
Grant
Filed:
July 8, 2016
Date of Patent:
October 20, 2020
Assignees:
PROTEOMETECH INC., KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
Inventors:
Eun Wie Cho, Chang Kyu Heo, Hai Min Hwang, Jeong Heon Ko, Kook Jin Lim, Hye Jung Lee
Abstract: Provided are an autoantibody specifically binding to an exosomal protein EIF3A (Eukaryotic translation initiation factor 3 subunit A) or a fragment including an antigen-binding site (paratope) thereof, a hybridoma cell line producing the autoantibody, a polypeptide having an amino acid sequence of an antigenic determinant (epitope) specifically binding to the autoantibody, a composition for diagnosing liver cancer including an agent measuring an expression level of the autoantibody or the fragment including the antigen-binding site thereof, a kit for diagnosing liver cancer including the composition, and a method of providing information for diagnosis of liver cancer by using the composition. Further, provided is a method of screening for a therapeutic agent for liver cancer by using an expression level of the autoantibody.
Type:
Application
Filed:
July 8, 2016
Publication date:
July 4, 2019
Applicants:
Korea Research Institute of Bioscience and Biotechnology, ProteomeTech Inc.
Inventors:
Eun Wie Cho, Chang Kyu Heo, Hai Min Hwang, Jeong Heon Ko, Kook Jin Lim, Hye Jung Lee
Abstract: Provided is a composition for detecting a protein, containing a tyrosine oxide-coupled biomaterial. Various diseases may be easily and rapidly diagnosed by easily detecting the composition containing a tyrosine oxide-coupled biomaterial according to the present invention, by identifying a color of the protein bound with a tyrosine oxide-coupled biomaterial prepared by binding tyrosine oxide, which is a natural pigment present in a living body, with the biomaterial. Accordingly, the composition of the present invention may be used to easily and rapidly diagnose various diseases in real time in an operating room, and may usefully replace conventional histological analysis without a secondary antibody reaction and a final operation of color expression.
Type:
Grant
Filed:
January 20, 2012
Date of Patent:
August 7, 2018
Assignee:
PROTEOMETECH INC.
Inventors:
Kook Jin Lim, Jin Ik Lim, Bum Joon Kim, Kyung Hwa Yoo, Soo Jung Park
Abstract: An apparatus for inspecting an antibiotic and a method for determining antibiotic sensitivity using the same is provided. The antibiotic susceptibility inspection time which has conventionally taken longer than 24 hours is shortened to about 2 hours or less, the efficacy of the target substance is monitored in real time, the identification of the microorganism, the kind of the antibiotic capable of treating the microorganism, and the minimum dosage thereof are quickly confirmed. Microbial infections requiring prompt diagnosis and treatment can be effectively treated.
Type:
Application
Filed:
August 14, 2017
Publication date:
February 15, 2018
Applicants:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, PROTEOMETECH INC.
Inventors:
Kyung Hwa YOO, Nal Ae HAN, Bong Jun KIM, Sun Mi LEE, Kook Jin LIM, Jeseung OH