Abstract: The invention provides antibodies to tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Grant
Filed:
September 30, 2022
Date of Patent:
January 14, 2025
Assignee:
Prothena Biosciences Limited
Inventors:
Peter Seubert, Philip James Dolan, III, Yue Liu, Robin Barbour
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
March 11, 2024
Publication date:
September 19, 2024
Applicant:
Prothena Biosciences Limited
Inventors:
Robin BARBOUR, Svetlana ALEXANDER, Mark E. RENZ, Shuning GAI, Tarlochan S. NIJJAR, Philip James DOLAN, III, Philip PAYNE
Abstract: The invention provides antibodies that specifically bind sortilin. The antibodies inhibit or delay pathologies associated with changes in progranulin levels and associated symptomatic deterioration.
Type:
Grant
Filed:
October 26, 2023
Date of Patent:
July 30, 2024
Assignee:
Prothena Biosciences Limited
Inventors:
Andriani Ioannou, Tarlochan S. Nijjar, Philip James Dolan, III, Wagner Zago
Abstract: The invention provides antibodies that specifically bind sortilin. The antibodies inhibit or delay pathologies associated with changes in progranulin levels and associated symptomatic deterioration.
Type:
Grant
Filed:
October 26, 2023
Date of Patent:
July 30, 2024
Assignee:
Prothena Biosciences Limited
Inventors:
Andriani Ioannou, Tarlochan S. Nijjar, Philip James Dolan, III, Wagner Zago
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
January 25, 2024
Publication date:
June 27, 2024
Applicant:
Prothena Biosciences Limited
Inventors:
Tarlochan S. Nijjar, Robin Barbour, Philip James Dolan, III, Yue Liu, Svetlana Alexander, Mark E. Renz
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Grant
Filed:
May 2, 2018
Date of Patent:
April 16, 2024
Assignee:
Prothena Biosciences Limited
Inventors:
Robin Barbour, Svetlana Alexander, Mark Renz, Shuning Gai, Tarlochan S. Nijjar, Philip James Dolan, III, Philip Payne
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Grant
Filed:
February 22, 2021
Date of Patent:
March 12, 2024
Assignee:
Prothena Biosciences Limited
Inventors:
Tarlochan S. Nijjar, Robin Barbour, Philip James Dolan, III, Yue Liu, Svetlana Alexander, Mark E. Renz
Abstract: The invention provides methods of treating taupathies such as Alzheimer's disease with antibodies that bind to human tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Abstract: The invention provides antibodies to tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
April 21, 2023
Publication date:
October 26, 2023
Applicant:
Prothena Biosciences Limited
Inventors:
Peter Seubert, Philip James Dolan, III, Yue Liu, Robin Barbour
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
February 17, 2023
Publication date:
August 10, 2023
Applicant:
Prothena Biosciences Limited
Inventors:
Robin Barbour, Philip James Dolan, III, Yue Liu, Svetlana Alexander, Mark E. Renz
Abstract: The invention provides antibodies to tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Grant
Filed:
October 29, 2019
Date of Patent:
May 9, 2023
Assignee:
Prothena Biosciences Limited
Inventors:
Peter Seubert, Philip James Dolan, III, Yue Liu, Robin Barbour
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Grant
Filed:
November 4, 2020
Date of Patent:
February 21, 2023
Assignee:
Prothena Biosciences Limited
Inventors:
Robin Barbour, Philip James Dolan, III, Yue Liu, Svetlana Alexander, Mark E. Renz
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
November 4, 2020
Publication date:
November 24, 2022
Applicant:
Prothena Biosciences Limited
Inventors:
Robin Barbour, Philip James Dolan, III, Yue Liu
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
February 7, 2020
Publication date:
September 1, 2022
Applicant:
PROTHENA BIOSCIENCES LIMITED
Inventors:
Philip James DOLAN, III, Tarlochan S. NIJJAR, Svetlana ALEXANDER, Robin BARBOUR, Stephen Jed TAM
Abstract: The present application discloses humanized 9E4 antibodies. The antibodies bind to human alpha synuclein and can be used for immunotherapy of Lewy body disease.
Type:
Grant
Filed:
June 16, 2020
Date of Patent:
May 31, 2022
Assignee:
PROTHENA BIOSCIENCES LIMITED
Inventors:
Jose William Saldanha, Tarlochan S. Nijjar
Abstract: The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration.
Type:
Application
Filed:
May 2, 2018
Publication date:
March 24, 2022
Applicant:
PROTHENA BIOSCIENCES LIMITED
Inventors:
Robin BARBOUR, Svetlana ALEXANDER, Mark RENZ, Shuning GAI, Tarlochan S. NIJJAR, Philip James DOLAN, III, Philip PAYNE