Patents Assigned to Protherics Medicines Development Limited
  • Patent number: 8637659
    Abstract: The present invention relates to a novel family of monosaccharide derivatives and disaccharide derivatives and to a method of preparation thereof. A mono- and disaccharide derivatives according to the invention comprises at least one fatty acid ester and may further comprise one or more anionic groups and are useful for, inter alia, medical, pharmaceutical, cosmetic and food applications.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: January 28, 2014
    Assignee: Protherics Medicines Development Limited
    Inventors: Lucas Alfonsus T. Hilgers, Anneke Georgine Blom
  • Patent number: 8052981
    Abstract: The present invention includes a formulation comprising a physiological salt solution, or an oil-in-water emulsion, or a water immiscible solid phase, and an adjuvant comprising one or more disaccharide derivatives derived from cellobiose, gentiobiose, lactose, lactulose, maltose, melibiose, sucrose or turanose, wherein at least four of the free hydroxyl groups of the disaccharide molecule have been modified such that the disaccharide derivative has: (i) at least 3, but not more than N-1, fatty acid ester groups, wherein each of the fatty acid ester groups is represented by a general formula of —O—C(?O)—(CH2)xCH3 wherein x is between 6 and 14, and (ii) at least one, but no more than N-1 anionic groups, wherein N is the number of hydroxyl groups of the disaccharide from which the derivative is derived and wherein the combined number of fatty acid esters and anionic groups does not exceed N.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: November 8, 2011
    Assignee: Protherics Medicines Development Limited
    Inventors: Lucas Alfonsus T. Hilgers, Anneke Georgine Blom
  • Patent number: 7777011
    Abstract: Synthetic polypeptides having at least one antigenic site of a prior protein, methods for their use and manufacture, antibodies raised against such polypeptides and diagnostic kits containing these polypeptides or antibodies.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: August 17, 2010
    Assignee: Protherics Medicines Development Limited
    Inventors: Robert Vincent Fishleigh, Barry Robson, Roger Paul Mee
  • Publication number: 20090105150
    Abstract: An angiotensin derivative comprising at least one angiotensin peptide moiety coupled to a peptide carrier-binding moiety which can be used for therapy and prophylaxis of conditions associated with the renin activated angiotensin system.
    Type: Application
    Filed: April 24, 2008
    Publication date: April 23, 2009
    Applicant: Protherics Medicines Development Limited
    Inventors: James Francis Glover, Arthur Rushton, Phillip John Morgan, Stephen Clinton Young
  • Patent number: 7378489
    Abstract: An angiotensin derivative comprising at least one angiotensin peptide moiety coupled to a peptide carrier-binding moiety which can be used for therapy and prophylaxis of conditions associated with the renin activated angiotensin system.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: May 27, 2008
    Assignee: Protherics Medicines Development Limited
    Inventors: James Francis Glover, Arthur Rushton, Phillip John Morgan, Stephen Clinton Young
  • Publication number: 20070243182
    Abstract: A method of combating toxicity caused by an antifolate compound of Formula I, in an individual who has been administered the compound. The method comprises administering an enzyme that has carboxypeptidase G activity to the individual.
    Type: Application
    Filed: February 28, 2005
    Publication date: October 18, 2007
    Applicant: Protherics Medicines Development Limited
    Inventors: Roger Melton, Anthony Atkinson