Patents Assigned to PROTIP MEDICAL
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Patent number: 11602578Abstract: The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.Type: GrantFiled: November 2, 2018Date of Patent: March 14, 2023Assignees: Université de Strasbourg, Institut National De La Sante Et De La Recherche Medicale (INSERM), Protip MedicalInventors: Philippe Lavalle, Pierre Schaaf, Nihal Engin Vrana, Angela Mutschler, Cynthia Calligaro, Lorène Tallet
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Patent number: 11471558Abstract: The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.Type: GrantFiled: May 2, 2017Date of Patent: October 18, 2022Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ DE STRASBOURG, PROTIP MEDICALInventors: Philippe Lavalle, Pierre Schaaf, Nihal Engin Vrana, Angela Mutschler
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Patent number: 10864296Abstract: A polyelectrolyte coating comprises at least one polycationic layer consisting of at least one polyarginine as herein defined and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit. Also disclosed is a method of preventing a bacterial infection in an individual.Type: GrantFiled: July 11, 2017Date of Patent: December 15, 2020Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ DE STRASBOURG, PROTIP MEDICALInventors: Philippe Lavalle, Pierre Schaaf, Nihal Engin Vrana, Angela Mutschler
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Patent number: 10449038Abstract: The invention relates to an intra-laryngeal prosthesis (PIL) for insertion into a larynx, said prosthesis PIL having an upper portion (PH) comprising: a tubular inner wall (1) with a first end, referred to as upper end (2), and a second end, referred to as lower end (3); a tubular outer wall (4) with a first end, referred to as upper end (2) and a second end, referred to as lower end (3), said outer wall (4) surrounding at least a portion of the inner wall (1); a plurality of ribs (5) extending in the direction of the main axis (X) of the prosthesis and connecting the inner wall (1) with the outer wall (4) such that a plurality of cells (6) are formed between the inner wall (1) and the outer wall (4).Type: GrantFiled: March 8, 2017Date of Patent: October 22, 2019Assignee: PROTIP MEDICALInventor: Nicolas Perrin
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Patent number: 9913713Abstract: The invention relates to an intralaryngeal prosthesis which is not at risk of getting blocked and which allows the patient to breathe comfortably. For this purpose, the prosthesis comprises a tubular body pierced by a proximal opening and a convex dome-shaped valve (10), the valve being arranged such that: the distal end (15) of the valve forms a rim (16) which covers a portion of the tubular body (2), and such that a space (17) exists between the distal end (15) of the valve and the tubular body (2) such that air can enter the proximal opening (8) of the tubular body through said space (17).Type: GrantFiled: September 5, 2014Date of Patent: March 13, 2018Assignee: PROTIP MEDICALInventors: Nicolas Perrin, Maurice Berenger