Patents Assigned to Protive Biotherapeutics, Inc.
  • COMPOSITIONS AND METHODS FOR SILENCING APOLIPOPROTEIN C-III EXPRESSION
    Publication number: 20120184595
    Abstract: The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA that target apolipoprotein C-III (APOC3) gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles (e.g., for the treatment of lipid diseases or disorders such as atherosclerosis or a dyslipidemia such as hypertriglyceridemia or hypercholesterolemia).
    Type: Application
    Filed: January 26, 2010
    Publication date: July 19, 2012
    Applicant: Protive Biotherapeutics, Inc.
    Inventors: Marcia MacDonald, Amy C.H. Lee, Ian MacLachlan