Abstract: A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
Type:
Application
Filed:
December 16, 2002
Publication date:
October 16, 2003
Applicant:
PROVASIS THERAPEUTICS, INC.
Inventors:
Robert E. Krall, Charles W. Kerber, Kimberly Knox
Abstract: A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
Type:
Grant
Filed:
May 23, 2000
Date of Patent:
March 25, 2003
Assignee:
Provasis Therapeutics, Inc.
Inventors:
Robert E. Krall, Charles W. Kerber, Kimberly Knox
Abstract: A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
Type:
Grant
Filed:
February 2, 2000
Date of Patent:
November 5, 2002
Assignee:
Provasis Therapeutics Inc.
Inventors:
Robert E. Krall, Charles W. Kerber, Kimberly Knox
Abstract: A composition useful as an embolic agent that selectively creates an embolic blockage in the lumen of a blood vessel, duct, fistula or other like body passageways by combining a monomer component and a second component wherein, said monomer component comprises of a alkyl cyanoacrylate monomer and at least one inhibitor agent; and said second component that functions as an opacificant agent and a polymerization retardant.
Type:
Grant
Filed:
January 29, 1999
Date of Patent:
November 5, 2002
Assignee:
Provasis Therapeutics Inc.
Inventors:
Robert E. Krall, Charles W. Kerber, Kimberly Knox