Patents Assigned to Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione—Instituto Dermopatico Dell'Immacolata
  • Peptide inhibiting platelet derived growth factor (PDGF-BB) and fibroblast growth factor (bFGF) activity
    Patent number: 7009036
    Abstract: A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. The molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC) The molecule is also able to inhibit in vivo angiogenesis CD1 mice.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: March 7, 2006
    Assignee: Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione—Instituto Dermopatico Dell'Immacolata
    Inventors: Antonio Facchiano, Francesco Facchiano, Angelo Facchiano