Abstract: A method for preparing an injectable plasma gel from a sample of centrifuged blood, comprising: provide a collection tube containing a sample of whole blood. Centrifuge and then heat the collection tube to create an upper layer of denatured plasma and a lower layer of denatured red blood cells. Providing an assembly including a syringe (or a syringe and a transfer tube attached to it) and a tube seal mounted on the distal end of the syringe, and the tube seal having an outer diameter which closely approximates the inner diameter of the tube. Inserting the distal end of the assembly into the heat resistant collection tube such that the tube seal abuts the layer of plasma gel. Advancing the assembly into the collection tube until all of the plasma gel layer is transferred into the hollow interior of the syringe barrel.

Abstract: A device for collecting blood, comprising: a tubular member having a diameter D1 enclosing an interior volume having a rated capacity, a distal end of the tubular member provided with a tip having a first through-hole in fluid communication with the interior volume, a proximal end of the tubular member provided a second through-hole in fluid communication with the interior volume; a cap formed of a self-healing material and configured to seal the tip of the tubular member; and a plunger movably accommodated within the interior volume of the tubular member, the plunger including an elongate member having an enlarged pad provided on a proximal end, an elastomeric member provided on a distal end and one or more locking wing members provided on and biased to extend away from the elongate member; wherein when the plunger is retracted to the rated capacity, the one or more locking wing members extend beyond the interior volume and engage with the proximal end of the tubular member.

Abstract: Device for cutting a syringe having a barrel with a flange at a proximal end thereof, the barrel containing a liquid, a plunger provided in the barrel and sealing the liquid specimen therein, said cutting device comprising: a jig for supporting a syringe, the jig including a proximal wall and a distal wall, a first through-hole defined in the proximal wall and a second through-hole defined in the distal wall; wherein the first and second through-holes are coaxially aligned and are sized to closely approximate the barrel; the first through-hole including a counter bore such that a distal end of the first through-hole closely approximates the barrel and a proximal end of the first through-hole closely approximates the syringe flange; a blade pivotably supported between the proximal and distal walls; wherein the blade cuts the proximal end of the syringe with the flanges without contaminating the liquid within the barrel.

Abstract: A device for collecting blood, comprising: a tubular member having a diameter D1 enclosing an interior volume having a rated capacity, a distal end of the tubular member provided with a tip having a first through-hole in fluid communication with the interior volume, a proximal end of the tubular member provided a second through-hole in fluid communication with the interior volume; a cap formed of a self-healing material and configured to seal the tip of the tubular member; and a plunger movably accommodated within the interior volume of the tubular member, the plunger including an elongate member having an enlarged pad provided on a proximal end, an elastomeric member provided on a distal end and one or more locking wing members provided on and biased to extend away from the elongate member; wherein when the plunger is retracted to the rated capacity, the one or more locking wing members extend beyond the interior volume and engage with the proximal end of the tubular member.

Abstract: Method for transferring one or more portions of fluid from a specimen tube, comprising: providing an elongate connector comprising an elongated tube having a lumen or through-hole extending between proximal and distal ends thereof, a Luer-compatible female taper provided on the proximal end of the connector, a flange provided proximate the distal end of the connector; providing a tube seal mounted on the distal end of the connector, the tube seal comprising an elastomeric member having a longitudinal axis, a proximal end, a distal end, and a through-hole extending therebetween, the distal end having a frustoconical or chamfered face forming a funnel, the elastomeric member having an outer diameter sized to sealingly engage with an inner surface of the specimen tube; advancing the distal end of the connector and the tube seal into the specimen tube, the funnel directing the first layer into the through-hole of the connector.

Abstract: Method for transferring one or more portions of fluid from a specimen tube, comprising: providing an elongate connector comprising an elongated tube having a lumen or through-hole extending between proximal and distal ends thereof, a Luer-compatible female taper provided on the proximal end of the connector, a flange provided proximate the distal end of the connector; providing a tube seal mounted on the distal end of the connector, the tube seal comprising an elastomeric member having a longitudinal axis, a proximal end, a distal end, and a through-hole extending therebetween, the distal end having a frustoconical or chamfered face forming a funnel, the elastomeric member having an outer diameter sized to sealingly engage with an inner surface of the specimen tube; advancing the distal end of the connector and the tube seal into the specimen tube, the funnel directing the first layer into the through-hole of the connector.

Abstract: Device for cutting a syringe having a barrel with a flange at a proximal end thereof, the barrel containing a liquid, a plunger provided in the barrel and sealing the liquid specimen therein, said cutting device comprising: a jig for supporting a syringe, the jig including a proximal wall and a distal wall, a first through-hole defined in the proximal wall and a second through-hole defined in the distal wall; wherein the first and second through-holes are coaxially aligned and are sized to closely approximate the barrel; the first through-hole including a counter bore such that a distal end of the first through-hole closely approximates the barrel and a proximal end of the first through-hole closely approximates the syringe flange; a blade pivotably supported between the proximal and distal walls; wherein the blade cuts the proximal end of the syringe with the flanges without contaminating the liquid within the barrel.

Abstract: A device for extracting plasma from a fluid collection tube comprising: a tubular barrel having sidewall surrounding a lumen which extends between proximal and distal ends thereof, the tubular barrel forming a tip at a distal end; a barrel seal movingly seated within the lumen of the tubular barrel, the barrel seal closing and sealing the proximal end of the tubular barrel; a tube seal having a proximal end, a distal end, and a lumen extending therebetween, the proximal end having a frustoconical or chamfered face, the tube seal having an outer diameter sized to sealingly engage with an inner surface of the fluid collection tube, and an inner diameter sized to sealingly engage with an outer surface of the tip of the tubular barrel, the tube seal mounted on the tubular barrel such that the tip of the tubular barrel extends into the tube seal lumen.

Abstract: Method for transferring one or more portions of fluid from a specimen tube, comprising: providing an elongate connector comprising an elongated tube having a lumen or through-hole extending between proximal and distal ends thereof, a Luer-compatible female taper provided on the proximal end of the connector, a flange provided proximate the distal end of the connector; providing a tube seal mounted on the distal end of the connector, the tube seal comprising an elastomeric member having a longitudinal axis, a proximal end, a distal end, and a through-hole extending therebetween, the distal end having a frustoconical or chamfered face forming a funnel, the elastomeric member having an outer diameter sized to sealingly engage with an inner surface of the specimen tube; advancing the distal end of the connector and the tube seal into the specimen tube, the funnel directing the first layer into the through-hole of the connector.

Abstract: A device for extracting plasma from a fluid collection tube comprising: a tubular barrel having sidewall surrounding a lumen which extends between proximal and distal ends thereof, the tubular barrel forming a tip at a distal end; a barrel seal movingly seated within the lumen of the tubular barrel, the barrel seal closing and sealing the proximal end of the tubular barrel; a tube seal having a proximal end, a distal end, and a lumen extending therebetween, the proximal end having a frustoconical or chamfered face, the tube seal having an outer diameter sized to sealingly engage with an inner surface of the fluid collection tube, and an inner diameter sized to sealingly engage with an outer surface of the tip of the tubular barrel, the tube seal mounted on the tubular barrel such that the tip of the tubular barrel extends into the tube seal lumen.