Patents Assigned to PSILO SCIENTIFIC LTD.
  • Patent number: 11957659
    Abstract: A transmucosal psychoactive alkaloid composition including a psychoactive alkaloid extract or synthetic psychoactive alkaloid. The alkaloids in the extract are predominantly dephosphorylated rather than phosphorylated. The transmucosal psychoactive alkaloid composition also includes a mucoadhesive polymer, a carrier, and optional further excipients. The non-ingestive composition may be taken orally through the mucosa. A process for obtaining an oral transmucosal psychoactive alkaloid composition includes dephosphorylating the alkaloid during extraction, purifying the extracted alkaloid and standardizing to a specific concentration by adding measured quantities of excipients.
    Type: Grant
    Filed: August 26, 2023
    Date of Patent: April 16, 2024
    Assignee: Psilo Scientific Ltd.
    Inventors: Ryan Moss, Benjamin Lightburn, Lisa Ranken
  • Patent number: 11786506
    Abstract: A transmucosal psychoactive alkaloid composition including a psychoactive alkaloid extract or synthetic psychoactive alkaloid. The alkaloids in the extract are predominantly dephosphorylated rather than phosphorylated. The transmucosal psychoactive alkaloid composition also includes a mucoadhesive polymer, a carrier, and optional further excipients. The non-ingestive composition may be taken orally through the mucosa. A process for obtaining an oral transmucosal psychoactive alkaloid composition includes dephosphorylating the alkaloid during extraction, purifying the extracted alkaloid and standardizing to a specific concentration by adding measured quantities of excipients.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: October 17, 2023
    Assignee: Psilo Scientific Ltd
    Inventors: Ryan Moss, Benjamin Lightburn, Lisa Ranken
  • Patent number: 11642385
    Abstract: This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: May 9, 2023
    Assignee: PSILO SCIENTIFIC LTD.
    Inventors: Benjamin Lightburn, Ryan Moss, Lisa Ranken
  • Patent number: 11571450
    Abstract: This invention relates to the extraction of psychoactive compounds from psilocybin fungus for use in medicine. Raw psilocybin fungus is dried and ground. The solvent used for extraction is a lower aliphatic alcohol, water, a hydro-alcohol mixture, an acidic hydro-alcohol mixture, or an alkaline hydro-alcohol mixture. The extraction slurry is filtered and pH-adjusted if necessary. The solvent is then partially evaporated, or completely evaporated with water added back, to form a concentrated slurry. The concentrated slurry is then standardized to provide a known concentration of the psychoactive alkaloids that have been extracted. The standardized slurry may then be dried to result in a powdered psilocybin mushroom extract with a precisely defined purity.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: February 7, 2023
    Assignee: PSILO SCIENTIFIC LTD
    Inventors: Benjamin Lightburn, Ryan Moss, Lisa Ranken
  • Patent number: 11510952
    Abstract: This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: November 29, 2022
    Assignee: PSILO SCIENTIFIC LTD.
    Inventors: Benjamin Lightburn, Ryan Moss, Lisa Ranken
  • Patent number: 11491138
    Abstract: The liquid composition includes a psychoactive alkaloid extract or synthetic psychoactive alkaloid. The alkaloids in the extract are predominantly dephosphorylated rather than phosphorylated. The injectable psychoactive alkaloid composition includes a carrier, an optional tonicity modifier, an optional antioxidant or preservative, an optional pH modifier, and optional further excipients. A process for obtaining an injectable psychoactive alkaloid composition includes dephosphorylating the alkaloid during extraction, purifying the extracted alkaloid, and standardizing it to a specific concentration by adding measured quantities of excipients.
    Type: Grant
    Filed: March 16, 2022
    Date of Patent: November 8, 2022
    Assignee: PSILO SCIENTIFIC LTD.
    Inventors: Ryan Moss, Benjamin Lightburn, Lisa Ranken
  • Patent number: 11382942
    Abstract: This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: July 12, 2022
    Assignee: PSILO SCIENTIFIC LTD.
    Inventors: Benjamin Lightburn, Ryan Moss, Lisa Ranken
  • Patent number: 11331357
    Abstract: This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: May 17, 2022
    Assignee: PSILO SCIENTIFIC LTD.
    Inventors: Benjamin Lightburn, Ryan Moss, Lisa Ranken
  • Patent number: 11298388
    Abstract: This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.
    Type: Grant
    Filed: September 23, 2021
    Date of Patent: April 12, 2022
    Assignee: PSILO SCIENTIFIC LTD.
    Inventors: Benjamin Lightburn, Ryan Moss, Lisa Ranken