Patents Assigned to PsiOxus Therapeutics Limited
  • Treatment of cachexia
    Patent number: 8716325
    Abstract: The present invention provides a means for prevention and treatment of cachexia and other chronic illnesses including but not limited to the promotion of weight gain, reduction or prevention of weight loss by administration of a substance that both reduces the sensitivity of beta-adrenergic receptors and of 5-HT1a receptors. (S)-pindolol, (S)-propranolol, tertatolol or bopindolol are preferred for this purpose.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: May 6, 2014
    Assignee: PsiOxus Therapeutics Limited
    Inventor: David Cavalla
  • Generation of replication competent viruses for therapeutic use
    Patent number: 8574594
    Abstract: The present invention relates to the generation of replication-competent viruses having therapeutic utility. The replication-competent viruses of the invention can express proteins useful in the treatment of disease.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: November 5, 2013
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Terry Hermiston, Fang Jin, Peter Kretschmer
  • CHIMERIC ADENOVIRUSES FOR USE IN CANCER TREATMENT
    Publication number: 20130230902
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: April 10, 2012
    Publication date: September 5, 2013
    Applicant: PsiOxus Therapeutics Limited
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • CHIMERIC ADENOVIRUSES FOR USE IN CANCER TREATMENT
    Publication number: 20130217095
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: April 15, 2013
    Publication date: August 22, 2013
    Applicant: PSIOXUS THERAPEUTICS LIMITED
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • CHIMERIC ADENOVIRUSES FOR USE IN CANCER TREATMENT
    Publication number: 20120231524
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: April 10, 2012
    Publication date: September 13, 2012
    Applicant: PsiOxus Therapeutics Limited
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • Generation of oncolytic adenoviruses and uses thereof
    Patent number: 8216819
    Abstract: The present invention relates to a method for the production of onolytic adenoviruses having increased potency and their therapeutic applications for cancer. Recombinant adenoviruses and methods to produce them are provided.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: July 10, 2012
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Terry Hermiston, Irene Kuhn
  • MULTI-VALENT ADJUVANT DISPLAY
    Publication number: 20120141409
    Abstract: The present invention provides an adjuvant-polymer construct comprising a polymer backbone which is covalently linked to 3 or more adjuvants, wherein the 3 or more adjuvants are each present in a pendant side chain, the adjuvants being connected to the polymer backbone either directly or via a spacer group.
    Type: Application
    Filed: May 7, 2010
    Publication date: June 7, 2012
    Applicant: PSIOXUS THERAPEUTICS LIMITED
    Inventors: Leonard Charles William Seymour, Kerry Fisher
  • PREVENTION AND TREATMENT OF SARCOPENIA
    Publication number: 20120095070
    Abstract: The present invention provides a means for prevention and treatment of sarcopenia by administration of a substance that both reduces the sensibility of beta-adrenergic receptors and of 5-HT1a receptors. (S)-pindolol, (S)-propanol, tertalol, or bopindolol are preferred for this purpose.
    Type: Application
    Filed: April 29, 2010
    Publication date: April 19, 2012
    Applicant: PSIOXUS THERAPEUTICS LIMITED
    Inventors: Jochen Springer, Stefan Anker, Andrew Coats, John Beadle
  • Chimeric adenoviruses for use in cancer treatment
    Patent number: 8158599
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: April 17, 2012
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn