Abstract: The present invention provides compounds of formula (I) wherein A, R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.
Type:
Grant
Filed:
April 13, 2018
Date of Patent:
January 5, 2021
Assignees:
Hoffmann-La Roche Inc., PTC Theranentics. Inc.
Inventors:
Hasane Ratni, Luke Green, Marla L. Weetall, Nikolai A. Naryshkin