Patents Assigned to Pulmatrix Operating Company, Inc.
  • Patent number: 11235112
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutics agents to patients.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: February 1, 2022
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • Patent number: 11173115
    Abstract: The present invention is directed toward respirable dry powders and particles for systemic delivery of pharmaceutically active agents or delivery to the respiratory tract. The dry powders contain one or more monovalent metal cations (such as Na+), are small and dispersible.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: November 16, 2021
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Jean C. Sung, Michael M. Lipp
  • Patent number: 11116722
    Abstract: The invention relates to dry powder formulations comprising respirable dry particles that contain 1) an antifungal agent in crystalline particulate form, 2) a stabilizer, and 3) one or more excipients.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: September 14, 2021
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Jason M. Perry, Jean C. Sung, David L. Hava, Robert Clifford Saunders, Hillary S. Bergson, Andrew Emmet O'Connor
  • Patent number: 10806871
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: October 20, 2020
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • Patent number: 10376465
    Abstract: The present invention is directed toward respirable dry powders and particles for systemic delivery of pharmaceutically active agents or delivery to the respiratory tract. The dry powders contain one or more monovalent metal cations (such as Na+), are small and dispersible.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: August 13, 2019
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Michael M. Lipp, Jean C. Sung
  • Patent number: 9744130
    Abstract: The invention relates to respirable dry particles that contain one or more divalent metal cations, such as magnesium, in an amount of less than 3% by weight, and to dry powders that contain the respirable particles. The dry particles can further contain an active agent, or can be used as carrier particles to deliver an active agent.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: August 29, 2017
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Michael M. Lipp, Jean C. Sung
  • Patent number: 9737518
    Abstract: The present invention relates to respirable dry powder comprising respirable dry particles that comprise sodium chloride, leucine, and tiotropium bromide, wherein the sodium chloride is about 60% to about 90%, the leucine is about 10% to about 40%, the tiotropium bromide is about 0.01% to about 0.5%, and optionally one or more additional therapeutic agents up to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%. The invention also relates to respirable dry powders that contain respirable dry particles that comprise sodium chloride, leucine, and tiotropium bromide, wherein the sodium chloride is 67% to 84%, the leucine is 12% to 28%, the tiotropium bromide is about 0.01% to about 0.5%, and optionally one or more additional therapeutic agents up to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: August 22, 2017
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Jean C. Sung, Diana Manzanedo, Jason M. Perry, Wesley Dehaan, Brian Trautman
  • Patent number: 9238005
    Abstract: The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: January 19, 2016
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Jean C. Sung, Michael M. Lipp
  • Patent number: 9119778
    Abstract: The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: September 1, 2015
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Jean C. Sung, Michael M. Lipp