Abstract: A device and method for reducing the area of a transdermal patch without altering its pharmacokinetic profile are provided. The area of a transdermal patch is reduced by aligning the patch at a location on a template which uniquely matches a dimension of the patch. The patch is then cut along a line defined by an edge of the template when the patch is at the aligned location. The template can be selected from a group of templates which correspond to the desired percentage of area reduction of the patch. A sizing template for proportionally reducing the size of a transdermal patch which is one of a group of orthogonal patches of differing sizes is also provided. The template comprises a planar member having a straight bottom edge and a stepped top edge. The width of each step on the top edge is configured to uniquely match the width of one of the transdermal patches in the group. The height of the step defines a cutting line on which the patch is to be cut to achieve a preselected percentage of size reduction.