Patents Assigned to Pulmonx
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Patent number: 11937913Abstract: A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.Type: GrantFiled: April 23, 2020Date of Patent: March 26, 2024Assignee: Pulmonx CorporationInventors: Srikanth Radhakrishnan, Surag Mantri, Ryan Olivera
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Patent number: 11931170Abstract: Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed.Type: GrantFiled: December 6, 2019Date of Patent: March 19, 2024Assignee: Pulmonx CorporationInventors: Ajit Nair, Son Gia, Roger Farhnoltz, Nikolai Aljuri
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Patent number: 11911145Abstract: Methods and systems for determining collateral ventilation are disclosed. Methods may comprise introducing a diagnostic catheter into a lung compartment via an assisted ventilation device, inflating the occluding member to isolate the lung compartment, and performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device. The diagnostic procedure comprises determining an exhaled volume from the isolated lung compartment over a predetermined period of time while the patient is ventilated via the assisted ventilation device. The presence collateral ventilation may be determined based on the exhaled volume from the isolated lung compartment over the predetermined period of time.Type: GrantFiled: June 30, 2021Date of Patent: February 27, 2024Assignee: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
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Publication number: 20240041362Abstract: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.Type: ApplicationFiled: October 17, 2023Publication date: February 8, 2024Applicant: Pulmonx CorporationInventors: Surag Mantri, Srikanth Radhakrishnan
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Publication number: 20240032866Abstract: Devices systems and methods are disclosed for removing secretions from the lumen of a functional assessment catheter for the lungs. The system comprises a flushing unit configured to deliver a clearing fluid to the lumen of the pulmonary catheter to remove debris, secretions, or moisture from the lumen or sensors.Type: ApplicationFiled: October 11, 2023Publication date: February 1, 2024Applicant: Pulmonx CorporationInventor: Lutz FREITAG
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Patent number: 11883029Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.Type: GrantFiled: July 19, 2022Date of Patent: January 30, 2024Assignee: Pulmonx CorporationInventors: Nikolai Aljuri, Rodney C. Perkins, Niyazi Beyhan
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Publication number: 20240008874Abstract: Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.Type: ApplicationFiled: June 8, 2023Publication date: January 11, 2024Applicant: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
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Patent number: 11857406Abstract: Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. An exemplary flow control device is configured to block fluid flow in the inspiratory direction and the expiratory direction at normal breathing pressures and allow fluid flow in the expiratory direction at higher than normal breathing pressures.Type: GrantFiled: November 15, 2022Date of Patent: January 2, 2024Assignee: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
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Patent number: 11819328Abstract: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.Type: GrantFiled: January 29, 2021Date of Patent: November 21, 2023Assignee: Pulmonx CorporationInventors: Surag Mantri, Srikanth Radhakrishnan
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Patent number: 11813085Abstract: Devices systems and methods are disclosed for removing secretions from the lumen of a functional assessment catheter for the lungs. The system comprises a flushing unit configured to deliver a clearing fluid to the lumen of the pulmonary catheter to remove debris, secretions, or moisture from the lumen or sensors.Type: GrantFiled: October 2, 2019Date of Patent: November 14, 2023Assignee: Pulmonx CorporationInventor: Lutz Freitag
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Patent number: 11696763Abstract: Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.Type: GrantFiled: August 6, 2019Date of Patent: July 11, 2023Assignee: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
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Publication number: 20230136081Abstract: Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. An exemplary flow control device is configured to block fluid flow in the inspiratory direction and the expiratory direction at normal breathing pressures and allow fluid flow in the expiratory direction at higher than normal breathing pressures.Type: ApplicationFiled: November 15, 2022Publication date: May 4, 2023Applicant: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
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Publication number: 20230000387Abstract: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.Type: ApplicationFiled: September 8, 2022Publication date: January 5, 2023Applicant: Pulmonx CorporationInventor: Surag MANTRI
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Publication number: 20230000497Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.Type: ApplicationFiled: July 19, 2022Publication date: January 5, 2023Applicant: Pulmonx CorporationInventors: Nikolai Aljuri, Rodney C. Perkins, Niyazi Beyhan
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Patent number: 11529224Abstract: Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. An exemplary flow control device is configured to block fluid flow in the inspiratory direction and the expiratory direction at normal breathing pressures and allow fluid flow in the expiratory direction at higher than normal breathing pressures.Type: GrantFiled: July 28, 2020Date of Patent: December 20, 2022Assignee: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
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Patent number: 11471069Abstract: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.Type: GrantFiled: April 11, 2022Date of Patent: October 18, 2022Assignee: Pulmonx CorporationInventor: Surag Mantri
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Patent number: 11413045Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.Type: GrantFiled: July 15, 2020Date of Patent: August 16, 2022Assignee: Pulmonx CorporationInventors: Nikolai Aljuri, Rodney C. Perkins, Niyazi Beyhan
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Publication number: 20220233095Abstract: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.Type: ApplicationFiled: April 11, 2022Publication date: July 28, 2022Applicant: Pulmonx CorporationInventor: Surag MANTRI
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Publication number: 20220202467Abstract: Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.Type: ApplicationFiled: March 16, 2022Publication date: June 30, 2022Applicant: Pulmonx CorporationInventors: Peter P. Soltesz, Nikolai Aljuri, Ajit Nair
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Publication number: 20220184332Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment. The invention further discloses a catheter with a transparent occlusion element at its tip that enables examination of the lung passageway through a viewing scope.Type: ApplicationFiled: March 7, 2022Publication date: June 16, 2022Applicant: Pulmonx CorporationInventors: Nikolai Aljuri, Rodney C. Perkins, Ryan Olivera, Hoang Nguyen, Srikanth Radhakrishnan, Niyazi Beyhan