Patents Assigned to Pulmonx Corporation
-
Patent number: 10631758Abstract: A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.Type: GrantFiled: July 17, 2015Date of Patent: April 28, 2020Assignee: Pulmonx CorporationInventors: Srikanth Radhakrishnan, Surag Mantri, Ryan Olivera
-
Publication number: 20200107776Abstract: Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed.Type: ApplicationFiled: December 6, 2019Publication date: April 9, 2020Applicant: Pulmonx CorporationInventors: Ajit Nair, Son Gia, Roger Farhnoltz, Nikolai Aljuri
-
Publication number: 20200038612Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment. The invention further discloses a catheter with a transparent occlusion element at its tip that enables examination of the lung passageway through a viewing scope.Type: ApplicationFiled: May 31, 2019Publication date: February 6, 2020Applicant: Pulmonx CorporationInventors: Nikolai Aljuri, Rodney C. Perkins, Ryan Olivera, Hoang Nguyen, Srikanth Radhakrishnan, Niyazi Beyhan
-
Publication number: 20200038086Abstract: Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.Type: ApplicationFiled: October 2, 2019Publication date: February 6, 2020Applicant: Pulmonx CorporationInventors: Peter P. Soltesz, Nikolai Aljuri, Ajit Nair
-
Publication number: 20200037958Abstract: Devices systems and methods are disclosed for removing secretions from the lumen of a functional assessment catheter for the lungs. The system comprises a flushing unit configured to deliver a clearing fluid to the lumen of the pulmonary catheter to remove debris, secretions, or moisture from the lumen or sensors.Type: ApplicationFiled: October 2, 2019Publication date: February 6, 2020Applicant: Pulmonx CorporationInventor: Lutz Freitag
-
Publication number: 20200030075Abstract: Devices, methods, and systems are provided for loading an implantable device into a container. One aspect of the loading system contains a loader element with a loading tunnel that is configured to gradually contract an implantable device into a compressed state of reduced size relative to an expanded state as the implantable device travels through the loading tunnel.Type: ApplicationFiled: June 10, 2019Publication date: January 30, 2020Applicant: Pulmonx CorporationInventors: Ryan Olivera, Hoang Nguyen
-
Publication number: 20200022706Abstract: Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.Type: ApplicationFiled: August 6, 2019Publication date: January 23, 2020Applicant: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
-
Patent number: 10517529Abstract: Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed.Type: GrantFiled: August 30, 2016Date of Patent: December 31, 2019Assignee: Pulmonx CorporationInventors: Ajit Nair, Son Gia, Roger Farhnoltz, Nikolai Aljuri
-
Publication number: 20190388034Abstract: The present invention provides systems, methods, devices and kits for assessing the level of pulmonary disease in individual lung compartments. A lung compartment comprises a subportion of a lung, such as a lobe, a segment or a subsegment, for example. By measuring individual lung compartments, the level of disease of the pulmonary system may be more precisely defined by determining values of disease parameters reflective of individual subportions or compartments of a lung. Likewise, compartments may be separately imaged to provide further measurement information. Once individual compartments are characterized, they may be compared and ranked based on a number of variables reflecting, for example, level of disease or need for treatment. Such comparison may be aided by simultaneous display of such variables or images on a visual display. Further, the same tests may be performed on the lung as a whole or on both lungs and to determine the affect of the diseased lung compartments on the overall lung performance.Type: ApplicationFiled: September 5, 2019Publication date: December 26, 2019Applicant: Pulmonx CorporationInventors: Robert Kotmel, Peter Soltesz, Anthony Wondka, Rodney Perkins
-
Publication number: 20190380619Abstract: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.Type: ApplicationFiled: June 5, 2019Publication date: December 19, 2019Applicant: Pulmonx CorporationInventor: Surag MANTRI
-
Patent number: 10478125Abstract: Devices systems and methods are disclosed for removing secretions from the lumen of a functional assessment catheter for the lungs. The system comprises a flushing unit configured to deliver a clearing fluid to the lumen of the pulmonary catheter to remove debris, secretions, or moisture from the lumen or sensors.Type: GrantFiled: March 3, 2014Date of Patent: November 19, 2019Assignee: Pulmonx CorporationInventor: Lutz Freitag
-
Patent number: 10470811Abstract: Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.Type: GrantFiled: October 24, 2016Date of Patent: November 12, 2019Assignee: Pulmonx CorporationInventors: Peter P. Soltesz, Nikolai Aljuri, Ajit Nair
-
Patent number: 10456562Abstract: Devices, methods, and systems are provided for sealing a lung region. The target lung compartment is accessed and isolated via an isolation catheter. Fluid is delivered into the target lung compartment such that the target compartment is pressurized and the fluid flows through the collateral flow channel. A sealing agent is injected into the isolated lung compartment such that the agent is carried by the fluid to the collateral flow channel, thereby sealing the collateral flow channel. Variables of air flow may be measured or analyzed prior to injection of the sealing agent, or the sealing agent may be introduced into the region after a suitable time has elapsed.Type: GrantFiled: January 20, 2016Date of Patent: October 29, 2019Assignee: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
-
Patent number: 10413244Abstract: The present invention provides systems, methods, devices and kits for assessing the level of pulmonary disease in individual lung compartments. A lung compartment comprises a subportion of a lung, such as a lobe, a segment or a subsegment, for example. By measuring individual lung compartments, the level of disease of the pulmonary system may be more precisely defined by determining values of disease parameters reflective of individual subportions or compartments of a lung. Likewise, compartments may be separately imaged to provide further measurement information. Once individual compartments are characterized, they may be compared and ranked based on a number of variables reflecting, for example, level of disease or need for treatment. Such comparison may be aided by simultaneous display of such variables or images on a visual display. Further, the same tests may be performed on the lung as a whole or on both lungs and to determine the affect of the diseased lung compartments on the overall lung performance.Type: GrantFiled: October 21, 2015Date of Patent: September 17, 2019Assignee: Pulmonx CorporationInventors: Robert Kotmel, Peter Soltesz, Anthony Wondka, Rodney Perkins
-
Patent number: 10413300Abstract: Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.Type: GrantFiled: June 14, 2016Date of Patent: September 17, 2019Assignee: Pulmonx CorporationInventors: Sri Radhakrishnan, Ryan Olivera
-
Patent number: 10350048Abstract: Devices, methods, and systems are provided for loading an implantable device into a container. One aspect of the loading system contains a loader element with a loading tunnel that is configured to gradually contract an implantable device into a compressed state of reduced size relative to an expanded state as the implantable device travels through the loading tunnel.Type: GrantFiled: December 14, 2017Date of Patent: July 16, 2019Assignee: Pulmonx CorporationInventors: Ryan Olivera, Hoang Nguyen
-
Patent number: 10314992Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment. The invention further discloses a catheter with a transparent occlusion element at its tip that enables examination of the lung passageway through a viewing scope.Type: GrantFiled: May 4, 2015Date of Patent: June 11, 2019Assignee: Pulmonx CorporationInventors: Nikolai Aljuri, Rodney C. Perkins, Ryan Olivera, Hoang Nguyen, Srikanth Radhakrishnan, Niyazi Beyhan
-
Patent number: 10314516Abstract: A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.Type: GrantFiled: May 19, 2016Date of Patent: June 11, 2019Assignee: Pulmonx CorporationInventor: Surag Mantri
-
Publication number: 20180353116Abstract: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.Type: ApplicationFiled: August 21, 2018Publication date: December 13, 2018Applicant: Pulmonx CorporationInventors: Surag Mantri, Srikanth Radhakrishnan
-
Patent number: 10076271Abstract: Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.Type: GrantFiled: July 23, 2014Date of Patent: September 18, 2018Assignee: Pulmonx CorporationInventors: Surag Mantri, Srikanth Radhakrishnan