Patents Assigned to Purdue Research Foundatioin
  • Oral administration of antigens
    Patent number: 5352448
    Abstract: An oral vaccine formulation is provided for stimulation of an immune response in gut-associated lymphoid tissues. The formulation comprises an enzymatically degradable antigen in a hydrogel matrix. In ruminant species, the vaccine formulation, upon oral administration, is formed to pass through the rumen without substantial hydration and then into the post-ruminal portion of the digestive tract where the antigen is released for contact with the gut-associated lymphoid tissue.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: October 4, 1994
    Assignee: Purdue Research Foundatioin
    Inventors: Terry L. Bowersock, Waleed S. W. Shalaby, William E. Blevins, Michel Levy, Kinam Park