Patents Assigned to Purdue Research Foundation
  • Nonpeptide HIV-1 protease inhibitors
    Patent number: 8791135
    Abstract: Novel compounds and compositions for treating patients in need of relief from HIV, AIDS, and AIDS-related diseases are described. Methods for treating HIV, AIDS, and AIDS-related diseases using the compounds described herein are also described.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: July 29, 2014
    Assignee: Purdue Research Foundation
    Inventor: Arun K. Ghosh
  • Process for preparing enriched glucan biomass materials
    Patent number: 8790904
    Abstract: The disclosure describes a process for the conversion of lignocellulosic biomass to ethanol utilizing a dicarboxylic acid such as maleic acid as an enzyme mimic to hydrolyze the hemicellulose and cellulose of the biomass. Controlling the condition of the maleic acid hydrolysis can selectively hydrolyze the hemicellulose giving as a result a liquid portion rich in xylose and a solid portion rich in glucan. The glucan can be further hydrolyzed to produce a glucose containing material. The sugar materials can be fermented to produce ethanol which is recovered. The dicarboxylic acid is then recovered from the residue left after the ethanol is removed from the fermentation material, and the recovered dicarboxylic acid is recycled to the beginning of the process to treat additional lignocellulosic biomass.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: July 29, 2014
    Assignees: Purdue Research Foundation, Bowen Engineering Corporation
    Inventors: Nathan Mosier, Michael R. Ladisch, Brian Stater, Bradley Spindler
  • System and method of measuring quasi-static force with a piezoelectric sensor
    Patent number: 8789426
    Abstract: A system and method employing a piezoelectric sensor for quasi-static force measurement substantially free of drift and with improved low-frequency response. The output signal from the sensor is sampled and integrated using digital techniques that include a drift compensation algorithm. The algorithm continually monitors the sensor output and estimates bias errors that will cause the output to drift.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: July 29, 2014
    Assignee: Purdue Research Foundation
    Inventors: Steven D. Pekarek, Kevin A. Rosenbaum
  • Tunable Cavity Resonator Including A Plurality of MEMS Beams
    Publication number: 20140203896
    Abstract: A tunable cavity resonator includes a substrate, a cap structure, and a tuning assembly. The cap structure extends from the substrate, and at least one of the substrate and the cap structure defines a resonator cavity. The tuning assembly is positioned at least partially within the resonator cavity. The tuning assembly includes a plurality of fixed-fixed MEMS beams configured for controllable movement relative to the substrate between an activated position and a deactivated position in order to tune a resonant frequency of the tunable cavity resonator.
    Type: Application
    Filed: June 3, 2013
    Publication date: July 24, 2014
    Applicant: Purdue Research Foundation
    Inventors: Dimitrios Peroulis, Adam Fruehling, Joshua Azariah Small, Xiaoguang Liu, Wasim Irshad, Muhammad Shoaib Arif
  • NANOELECTROMECHANICAL RESONATORS
    Publication number: 20140203796
    Abstract: A silicon device, e.g., a nanoelectromechanical resonator, has a silicon substrate; an oxide layer having a trench therein; a silicon device layer over the oxide layer; and a nanowire disposed at least partly over the trench. Substantially no oxide or polysilicon is over the nanowire in the trench. A polyimide layer over the silicon device layer includes an opening over the trench. A silicon device can include silicon-on-insulator layers and at least one complementary metal-oxide semiconductor transistor in addition to a nanowire substantially suspended over a trench. A system for measurement of a nanoresonator includes an AC source in series with the nanoresonator to provide an electrical signal thereto at a selected first frequency. Electrode(s) adjacent to and spaced apart from the nanoresonator are driven by voltage source. A detector detects a current through the nanoresonator.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 24, 2014
    Applicant: Purdue Research Foundation
    Inventors: Saeed Mohammadi, Hossein Pajouhi, Jeffrey Frederick Rhoads, Lin Yu
  • LOW-COST PROCESS-INDEPENDENT RF MEMS SWITCH
    Publication number: 20140202837
    Abstract: A MEMS switch includes a semiconductor substrate, a movable cantilever and a cantilever anchor. The semiconductor substrate includes a device layer and a handle. The movable cantilever is formed in the semiconductor substrate, and is disposed over a void in the handle. The cantilever anchor is formed in the semiconductor substrate and defines a side wall of the void. A metal portion is formed on at least a portion of the movable cantilever. A metal contact is formed proximate an end of the movable cantilever. A biasing metal contact is formed adjacent the cantilever. The biasing metal contact is electrically disconnected from the metal contact.
    Type: Application
    Filed: September 6, 2013
    Publication date: July 24, 2014
    Applicant: Purdue Research Foundation
    Inventors: Adam Joseph Fruehling, Dimitrios Peroulis
  • System and method of iterative image reconstruction for computed tomography
    Patent number: 8787521
    Abstract: A system and method include acquisition of a set of image data corresponding to a time period of data acquisition, the set of image data corresponding to a plurality of voxels, wherein each of the plurality of voxels corresponds to a distinct acquisition time within the time period of data acquisition. The system and method further include the modeling of the plurality of voxels as a function of time based on a plurality of kinetic parameters associated therewith and reconstruction of an image from the set of image data based on the modeled plurality of voxels.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: July 22, 2014
    Assignees: General Electric Company, University of Notre Dame du Lac, Purdue Research Foundation
    Inventors: Jean-Baptiste Thibault, Bruno Kristiaan Bernard De Man, Kai Zeng, Zhou Yu, Charles Addison Bouman, Jr., Ken David Sauer
  • Method for codebook design and beamforming vector selection in per-user unitary rate control (PU2RC) system
    Patent number: 8787469
    Abstract: A base station includes a storage unit to store a codebook, wherein the codebook includes a plurality of matrices; a control unit to perform beamforming using the codebook to generate a signal; and a multi-antenna to transmit the signal. For all of the plurality of matrices, all column vectors of a same matrix of the plurality of matrices are orthogonal to each other. For all columns of the plurality of matrices, all column vectors of a same column of all of the plurality of matrices satisfy a Grassmannian line packing (GLP) criterion.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: July 22, 2014
    Assignees: Samsung Electronics Co., Ltd., Purdue Research Foundation
    Inventors: Sung Jin Kim, Bruno Clerckx, Seung Young Park, David J. Love, Il Han Kim
  • Systems and methods for analyzing a sample
    Patent number: 8785846
    Abstract: The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides systems for analyzing a sample that include an electric source, a vacuum chamber including a conducting member, in which the conducting member is coupled to the electric source, a sample introduction member coupled to the vacuum chamber, and a mass analyzer. The system is configured such that a distal end of the sample introduction member resides within the vacuum chamber and proximate the conducting member, such that an electrical discharge may be produced between the sample introduction member and the conducting member. A neutral gas that has been introduced into the vacuum chamber interacts with the generated discharge, producing ions within the vacuum chamber that are subsequently transferred into the mass analyzer in the vacuum chamber.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: July 22, 2014
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, Chen Tsung-Chi
  • Vehicles, power electronics modules and cooling apparatuses with single-phase and two-phase surface enhancement features
    Patent number: 8786078
    Abstract: Jet-impingement, two-phase cooling apparatuses and power electronics modules having a target surface with single- and two-phase surface enhancement features are disclosed. In one embodiment, a cooling apparatus includes a jet plate surface and a target layer. The jet plate surface includes a jet orifice having a jet orifice geometry, wherein the jet orifice is configured to generate an impingement jet of a coolant fluid. The target layer has a target surface, single-phase surface enhancement features, and two-phase surface enhancement features. The target surface is configured to receive the impingement jet, and the single-phase surface enhancement features and the two-phase enhancement features are arranged on the target surface according to the jet orifice geometry.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: July 22, 2014
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., Purdue Research Foundation
    Inventors: Matthew Joseph Rau, Ercan Mehmet Dede, Shailesh N. Joshi, Suresh V. Garimella
  • System and method of organism identification
    Patent number: 8787633
    Abstract: A system and method for identifying organisms by analysis of scattergrams of colonies is disclosed. cattergrams are obtained by culturing samples and illuminating the resultant colonies by a laser. The forward scattered light is imaged and subject to a feature extraction process. The feature vector may include Zernike or Chebyshev moments and may also include Harelick texture features. Feature vectors may be used to train a classification process using either supervised or unsupervised machine learning techniques. The classification process may be used to associate a colony phenotype with the genotype of the sample.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: July 22, 2014
    Assignee: Purdue Research Foundation
    Inventors: J. Paul Robinson, Bartlomiej Rajwa, Bulent Bayraktar, Arun K. Bhunia, E. Daniel Hirleman, Euiwon Bae
  • METHOD AND SYSTEM OF VACUUM ASSISTED RESIN TRANSFER MOLDINGS FOR REPAIR OF COMPOSITE MATERIALS AND STRUCTURE
    Publication number: 20140196833
    Abstract: The present disclosure provides a method of repairing a damaged portion of a panel formed of composite material. The method includes preparing the damaged portion for repair and applying a pressure responsive adhesive layer to substantially cover the damaged portion. The method also includes disposing a vacuum-assisted resin transfer molding repair patch assembly to substantially cover the damaged portion and substantially covering the repair patch assembly with a vacuum bag assembly. Resin is introduced into and impregnates the repair patch assembly. The repair patch assembly is cured after being impregnated.
    Type: Application
    Filed: May 4, 2012
    Publication date: July 17, 2014
    Applicant: Purdue Research Foundation
    Inventors: Pipes R. Byron, Ian Cameron Coker, Douglas Edward Adams, Ronald Sterkenburg, Jeffrey P. Youngblood
  • FAILURE REPAIR SEQUENCE GENERATION FOR NODAL NETWORK
    Publication number: 20140198630
    Abstract: Failure repair sequence generation systems and methods may generate a repair sequence for nodes experiencing failure in a nodal-network-based system that meets acceptable performance metrics, such as acceptable total network damage, acceptable node-failure preventability rate, or a combination thereof.
    Type: Application
    Filed: January 16, 2014
    Publication date: July 17, 2014
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Shimon Y. NOF, Xin CHEN
  • DYNAMIC LOAD-ABSORBING MATERIAL AND ARTICLES
    Publication number: 20140196998
    Abstract: Dynamic load-absorbing materials suitable for use as cushion-type and armor-type materials, for example, of types that can be incorporated into protective gear, equipment, armor, vehicles, and various other structures, or used for the isolation and dissipation of vibratory loads, such as vibration isolators used to support avionic equipment. The impact-absorbing materials include a matrix material (22) and at least first and second sets of inclusions (which can be either included material or voids) (24) in the matrix material (22) that define a hierarchy of inclusions (24) in the matrix material (22). The inclusions (24) differ in size, quantity, shape and/or composition in a direction through the impact-absorbing material, the combination of which contributes to the ability of the material to exhibit at least one property that changes as the inclusions (24) are deformed under load.
    Type: Application
    Filed: March 8, 2014
    Publication date: July 17, 2014
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Eric Allen Nauman, Evan Louis Breedlove, Anne Dye Zakrajsek, Eric S. Lynch
  • Coiled and microchannel heat exchangers for metal hydride storage systems
    Patent number: 8778063
    Abstract: Various apparatus and methods for exchanging heat from a solid to a liquid. Some embodiments pertain to removing heat from a pressure vessel in which a gas absorption reaction is occurring. Yet other embodiments pertain to pressure vessels in which hydrogen is being absorbed into a metal hydride.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: July 15, 2014
    Assignee: Purdue Research Foundation
    Inventors: Issam Mudawar, Milan Visaria
  • Endoscopic imaging device
    Patent number: 8777846
    Abstract: An endoscopic imaging device for endoscopy in a body vessel is disclosed. The device comprises an annular illumination tube comprising an annular illumination fiber for illuminating a body vessel during endoscopy. The device further includes a first imaging tube comprising a first imaging fiber for gross examination and navigation through the body vessel. The first imaging fiber is disposed within the annular illumination tube. The device further comprises a second imaging tube comprising a second imaging fiber for cellular imaging. The second illumination fiber is disposed adjacent the first imaging tube and within the annular illumination tube.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: July 15, 2014
    Assignee: Purdue Research Foundation
    Inventors: Joseph P. Robinson, Silas J. Leavesley, Peng Xi
  • MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME
    Publication number: 20140194383
    Abstract: Described herein are monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.
    Type: Application
    Filed: April 9, 2012
    Publication date: July 10, 2014
    Applicants: Cornell University, Coferon, Inc., Purdue Research Foundation
    Inventors: Francis Barany, Maneesh Pingle, Donald E. Bergstrom, Sarah F. Giardina, Lee Daniel Arnold
  • VEHICLES, POWER ELECTRONICS MODULES AND COOLING APPARATUSES WITH SINGLE-PHASE AND TWO-PHASE SURFACE ENHANCEMENT FEATURES
    Publication number: 20140192485
    Abstract: Jet-impingement, two-phase cooling apparatuses and power electronics modules having a target surface with single- and two-phase surface enhancement features are disclosed. In one embodiment, a cooling apparatus includes a jet plate surface and a target layer. The jet plate surface includes a jet orifice having a jet orifice geometry, wherein the jet orifice is configured to generate an impingement jet of a coolant fluid. The target layer has a target surface, single-phase surface enhancement features, and two-phase surface enhancement features. The target surface is configured to receive the impingement jet, and the single-phase surface enhancement features and the two-phase enhancement features are arranged on the target surface according to the jet orifice geometry.
    Type: Application
    Filed: December 30, 2013
    Publication date: July 10, 2014
    Applicants: PURDUE RESEARCH FOUNDATION, Toyota Motor Engineering & Manufacturing North America, Inc.
    Inventors: Matthew Joseph Rau, Ercan Mehmet Dede, Shailesh N. Joshi, Suresh V. Garimella
  • Low temperature plasma probe and methods of use thereof
    Patent number: 8772710
    Abstract: The present invention generally relates to a low temperature plasma probe for desorbing and ionizing at least one analyte in a sample material and methods of use thereof. In one embodiment, the invention generally relates to a low temperature plasma probe including: a housing having a discharge gas inlet port, a probe tip, two electrodes, and a dielectric barrier, in which the two electrodes are separated by the dielectric barrier, in which application of voltage from a power supply generates a low temperature plasma, and in which the low temperature plasma is propelled out of the discharge region by the electric field and/or the discharge gas flow.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: July 8, 2014
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, Jason Harper, Nicholas Charipar, Robert Graham Cooks
  • Methods and apparatus to model end-to-end class of service policies in networks
    Patent number: 8775352
    Abstract: Methods and apparatus to model end-to-end class of service policies in operational networks are disclosed. An example method to generate a class of service model is described, including electronically generating a ruleset based on the class of service configuration associated with a router, electronically generating a flat representation of the ruleset, electronically generating a class of service model by composing the flat representation into a composed ruleset, and storing the class of service model in a computer-readable memory.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: July 8, 2014
    Assignees: AT&T Intellectual Property I, L.P., Purdue Research Foundation
    Inventors: Subhabrata Sen, Carsten Lund, Sanjay Gopinatha Rao, Yu-Wei Sung