Abstract: A fuel for splitting water into hydrogen and an oxide component comprises a substantially solid pellet formed from a solid-like mixture of a solid-state source material capable of oxidizing in water to form hydrogen and a passivation surface layer of the oxide component, and a passivation preventing agent that is substantially inert to water in an effective amount to prevent passivation of the solid-state material during oxidation. The pellets are brought into contact with an alloy of the passivation preventing agent having a melting point temperature below that of the solid-like mixture to initiate the hydrogen-producing reaction at a lower temperature.

Abstract: A desorption atmospheric pressure chemical ionization (DAPCI) system delivers a primary ion beam composed of an inert, high velocity gas and solvent ions to a surface to effect desorption and ionization of both volatile and non-volatile species present on surfaces. A electrode having a tapered tip is connected to a high voltage power supply. The tapered tip projects outward from a capillary carrying a high-speed flow of gas. A vapor of a solvent is mixed into the annular gas flow surrounding the needle. The gaseous solvent vapor is ionized in close proximity to the tapered tip by virtue of the high voltage applied to the electrode. The high-speed flow of gas and solvent vapor ions extending outward from the capillary is directed toward a substrate on which an analyte of interest may have been deposited.

Abstract: Methods and apparatus that provide grade-level RF transceivers for use in trans-grade wireless communication networks. The methods involve incorporating slot antennas into grade-level opening covers, such as manhole covers, to provide built-in antennas for transceivers that may be connected by transmission lines. The grade-level transceivers use coupling mechanisms to connect transceivers to the slot antennas by way of transmission feed lines. Multi-slot grade-level transceivers use switching mechanisms to switch between multiple slot antennas. Certain embodiments may also include adaptable RF circuitry. Trans-grade wireless communication networks use these grade-level transceivers to communicate between below-ground and above-ground portions of the network, which may be used in underground utility systems such as combined sewer systems.

Abstract: A multi-modal data acquisition system for detecting target material on a biological reaction surface, the system comprising a radiation source for generating an incoming beam that impinges on the biological reaction surface at an oblique incidence angle and produces a reflected beam, an interferometric detector for detecting an interferometric signal from the illuminated surface, the reflected beam being directed to the interferometric detector, a fluorescence detector for detecting a fluorescence signal from the illuminated surface; the fluorescence detector being positioned to substantially minimize the incidence of the reflected beam; and a processing system for receiving the interferometric and fluorescence signals and determining the presence or absence of target material on the biological reaction surface. A reaction surface conditioned for the simultaneous collection of fluorescence, interferometric and other signals.

Abstract: Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for targeting prostate cancer cells. Also described herein are compositions containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

Abstract: An agent based model system provides simulation of the influence of environmental variables and tendencies in individual and social decision making relating to the formation of coalitions and ethnic groups. The system is based on improved understandings of human decision making under risk, and incorporates recent theoretical developments and computational tools. The system gives analysts the ability to predict the development of coalitions and ethnic groups, as well as the ability to manage the behavior of individuals in such groups. The model results provide confidence intervals for various possible scenarios in a mix of agents' decision rules and distribution of environmental resources. Applications include management of ethnic groups and violent conditions in unstable nations, the tracking of terrorist organizations, development of coalitions and oligopolies in business, and the modeling and interdiction of criminal organizations.

Abstract: The present disclosure provides a novel system and method for evaporating and ionizing compounds comprising an LIAD source and an ionization source that operates at atmospheric pressure. This system is readily adaptable for use with most commercially available mass spectrometers. Ionization sources include Atmospheric Pressure Chemical Ionization sources (APCI) and Atmospheric Pressure Photo Ionization (APPI) sources. The ionization sources are positioned such that the analyte desorbing from the surface of the LIAD is fed into the ion stream produced by the ionization source and ionized analyte and ionized fragments of the analyte are fed into the sample inlet of a mass spectrometer. These systems allow for the mass spectrometric analysis of non-polar compounds that lack readily ionizable functional groups, such as saturated and unsaturated hydrocarbons and compounds with medium to low polarity, as well as hydrocarbon mixtures, such as petroleum.

Abstract: N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof.

Abstract: Laser assisted machining process and machine utilizing multiple distributed laser units that are strategically distributed around the workpiece being machined to simultaneously heat the workpiece, creating a desired temperature distribution for laser assisted machining. Sequential incremental heating from different directions and positions are used, resulting in longer tool life and shorter machining time.

Abstract: A power converter is provided for an energy harvesting system of a micro-scale electronic device. The power converter is configured to transfer electrical energy from an energy transducer to an energy storage device. The power converter illustratively includes a tree topology charge pump.

Abstract: An intermediate product in the fabrication of a MOSFET, including a silicon carbide wafer having a substrate and a drift layer on said substrate, said drift layer having a plurality of source regions formed adjacent an upper surface thereof; a first oxide layer on said upper surface of said drift layer; a plurality of polysilicon gates above said first oxide layer, said plurality of polysilicon gates including a first gate adjacent a first of said source regions; an oxide layer over said first source region of greater thickness than said first oxide layer; and, an oxide layer over said first gate of substantially greater thickness than said oxide layer over said first source region.

Abstract: A method of acquiring a signal includes generating a first set of acquired signal power values comprising an acquired signal power value for each of a plurality of Doppler bins over a first predetection integration time (PIT) interval, and generating a second set of acquired signal power values comprising an acquired signal power value for each of the plurality of Doppler bins over a second subsequent PIT interval. The first and the second sets are used to generate at least three additional sets of acquired signal power values. A new set is generated by selecting the maximum of the summations for each Doppler bin from the three additional sets, and a Doppler shift is identified from the Doppler bin having the maximum summation value. The output may be used to initialize a first and a second extended Kalman filters for tracking a carrier signal and a code signal, respectively.

Abstract: Methods for detecting and evaluating the quality of protein crystals are provided comprising subjecting a sample to second order non-linear optical imaging and detecting the second harmonic generation signal.

Abstract: A microfluidic purge valve in a microfluidics system includes a notch defined in the valve seat of a microfluidic valve. The notch is sized so that gas entrained within a liquid pumped through the microfluidics system can pass freely therethrough but the liquid cannot. The notch is sized so that the resistant force generated by the surface tension of the liquid is equal to or greater than the force generated by the fluid pressure.

Abstract: The identification of a stable dw3 allele and development of molecular DNA markers to facilitate selection of this allele in development of new cultivars provides a simple genetic solution to the problem of tall height mutants in commercial sorghum [Sorghum bicolor (L.) Moench] parent lines and hybrids.

Abstract: An enhanced torque ripple mitigation algorithm for permanent magnet synchronous machines (PMSMs), the algorithm including compensation for sensor delay.

Abstract: This invention relates to a method of biocatalytically producing compounds that are commercially valuable but are detrimental to the host cells' development. The transgenic plants produced in accordance with the present invention comprise a novel controlled expression system comprising a promoter (2), a blocking sequence (a), and a structural gene (6), wherein the blocking sequence (a) is flanked by a pair of directly repeated site-specific recombination sequences (4). The blocking sequence (a) prevents expression of the structural gene (6) until removal of the blocking sequence (a) by site-specific recombinase activity encoded by a site-specific recombinase gene (12).

Abstract: A tissue graft composition comprising liver basement membrane is described. The graft composition can be implanted to replace or induce the repair of damaged or diseased tissues.

Abstract: A system and method employing a piezoelectric sensor for quasi-static force measurement substantially free of drift and with improved low-frequency response. The output signal from the sensor is sampled and integrated using digital techniques that include a drift compensation algorithm. The algorithm continually monitors the sensor output and estimates bias errors that will cause the output to drift.

Abstract: A molding process and apparatus suitable for use in molding processes, including rapid prototyping processes and short run production processes. The molding process and apparatus entail the use of a reconfigurable screen tool having a housing defining a manifold cavity and a plurality of substantially parallel pins, each having a head protruding from the housing and a shank protruding into the housing. The heads of the pins define a screen surface through which air is able to flow, for example, through gaps between adjacent heads or through internal passages within the pins. The process further includes axially moving the pins to configure the screen surface, preventing further axial movement of the pins relative to each other, and then drawing a vacuum within the manifold cavity and creating a vacuum at the screen surface.