Abstract: The present disclosure relates to polymorphs of D9-THC-naphthoylester for the preparation of D9-Tetrahydrocannabinol in high yields and high purity, methods of preparing the D9-Tetrahydrocannabinol, and compositions comprising the D9-Tetrahydrocannabinol.

Abstract: The present disclosure relates to the preparation of synthetic cannabinol and homologs thereof having the structure of Formula (I), wherein, n is 1, 2, 3 or 4. The methods described herein provide for high yields and purity in a one-pot synthesis or high yields and purity without the need for lengthy column chromatography. The present disclosure also relates to solid forms of cannabinol.

Abstract: The present disclosure relates to the preparation of a highly pure cannabidiol compound by a novel synthesis route. The cannabidiol compound can be prepared by an acid-catalyzed reaction of a di-halo olivetol with menthadienol, followed by two crystallization steps. The highly pure cannabidiol compound is produced in high yield, stereospecificity, or both, and shows exceedingly low levels of ?-9-tetrahydrocannabinol at the time of preparation and after storage.

Abstract: The present disclosure relates to a cannabidiol compound and compositions thereof and processes for preparing the compound and compositions. The processes include an acid-catalyzed reaction of a suitably selected and substituted di-bromo-olivetol or derivative thereof with a suitably selected and substituted cyclic alkene to produce a dibromo-cannabidiol compound or derivative thereof. The dibromo-cannabidiol compound or derivative thereof can be produced in high yield, high stereospecificity, or both. It can then be converted under reducing conditions to a cannabidiol compound or derivatives thereof.