Abstract: Disclosed are methods by which compounds/molecules capable of binding antigens, for example antibody type compounds/molecules, can be purified, extracted and/or selected. The methods may be used to purify, extract or select a specific type (or types) of binding agent from a mixed composition. The methods may be used to extract or purify specific binding agents from mixed compositions, which compositions comprise other agents capable of binding other antigens. The methods may find particular application as methods for the purification of blood group antigen antibodies.
Type:
Grant
Filed:
November 25, 2016
Date of Patent:
May 17, 2022
Assignee:
QBD (QS-IP) LIMITED
Inventors:
Neil Renault, Andrew Gordon Robb, Janine Scott Robb, David Cooper Robson
Abstract: The present invention is based on the finding that red blood cell antigens can be exploited as a means to detect red blood cells/erythrocytes. Specifically, by identifying red blood cell antigens which are expressed by substantially all red blood cell types, it is possible to provide a method which achieves the reliable detection of red blood cells.
Type:
Grant
Filed:
February 20, 2015
Date of Patent:
April 7, 2020
Assignee:
QBD (QS-IP) Limited
Inventors:
Janine Scott Robb, Andrew Gordon Robb, David Cooper Robson
Abstract: The present invention provides novel methods for the detection of antibodies, in particular, blood group antibodies. The methods of this invention may be applied to pre-transfusion blood compatibility testing for the detection of incompatibility between donor units (comprising donor red blood cells (erythrocytes)) and a recipient.
Type:
Grant
Filed:
February 6, 2015
Date of Patent:
December 25, 2018
Assignee:
QBD (QS-IP) LIMITED
Inventors:
Janine Scott Robb, David Cooper Robson, Neil Kevin Renault, Christopher Robert James Claxton