Abstract: Disclosed herein are system, method, and computer program product embodiments for aiding in the interpretation of variants observed in clinical sequencing data. An embodiment operates by receiving clinical trial enrollment criteria from a user, including but not limited to genetic targeting criteria; searching a knowledge base of patient test information received from a plurality of independent entities for patients that match the clinical trial enrollment criteria; and providing to the user search results for consented patients that match the clinical trial enrollment criteria.
Type:
Application
Filed:
May 18, 2020
Publication date:
September 3, 2020
Applicants:
QIAGEN Redwood City, Inc., QIAGEN GmbH
Inventors:
Douglas E. BASSETT, JR., Daniel R. Richards, Peer M. Schatz
Abstract: Disclosed herein are system, method, and computer program product embodiments for building a community database of allele counts. An embodiment operates by receiving human variant datasets derived from samples generated by distinct users, wherein the users consented to share pooled variant observations with other users; determining that a plurality of variant observations meet the inclusion criteria for a pool; and calculating one or more anonymized allele statistics from the pool.
Type:
Application
Filed:
May 18, 2020
Publication date:
September 3, 2020
Applicants:
QIAGEN Redwood City, Inc, QIAGEN GmbH
Inventors:
Douglas E. Bassett, JR., Daniel R. Richards, Peer M. Schatz
Abstract: Disclosed herein are system, method, and computer program product embodiments for aiding in the interpretation of variants observed in clinical sequencing data. An embodiment operates by receiving clinical trial enrollment criteria from a user, including but not limited to genetic targeting criteria; searching a knowledge base of patient test information received from a plurality of independent entities for patients that match the clinical trial enrollment criteria; and providing to the user search results for consented patients that match the clinical trial enrollment criteria.
Type:
Grant
Filed:
June 30, 2014
Date of Patent:
May 26, 2020
Assignees:
QIAGEN Redwood City, Inc., QIAGEN GmbH
Inventors:
Douglas E. Bassett, Jr., Daniel R. Richards, Peer M. Schatz
Abstract: Disclosed herein are system, method, and computer program product embodiments for building a community database of allele counts. An embodiment operates by receiving human variant datasets derived from samples generated by distinct users, wherein the users consented to share pooled variant observations with other users; determining that a plurality of variant observations meet the inclusion criteria for a pool; and calculating one or more anonymized allele statistics from the pool.
Type:
Grant
Filed:
August 15, 2014
Date of Patent:
May 19, 2020
Assignees:
QIAGEN Redwood City, Inc., QIAGEN GmbH
Inventors:
Douglas E. Bassett, Jr., Daniel R. Richards, Peer M. Schatz
Abstract: Methods for identifying disease-related pathways that can used to identify drug discovery targets, to identify new uses for known drugs, to identify markers for drug response, and related purposes.
Type:
Grant
Filed:
June 10, 2013
Date of Patent:
October 22, 2019
Assignee:
QIAGEN Redwood City, Inc.
Inventors:
Richard O. Chen, Raymond J. Cho, Ramon M. Felciano, Bret Holley, Viresh Patel, Daniel R. Richards, Sushma Selvarajan, Keith Steward, Sara Schneider
Abstract: Methods for identifying disease-related pathways that can be used to identify drug discovery targets, to identify new uses for known drugs, to identify markers for drug response, and related purposes.
Type:
Grant
Filed:
July 28, 2014
Date of Patent:
June 26, 2018
Assignee:
QIAGEN Redwood City, Inc.
Inventors:
Richard O. Chen, Raymond J. Cho, Ramon M. Felciano, Bret Holley, Viresh Patel, Daniel R. Richards, Sushma Selvarajan, Keith Steward, Sara Tanenbaum Schneider
Abstract: Disclosed herein are system, method, and computer program product embodiments for building a community database of allele counts. An embodiment operates by receiving human variant datasets derived from samples generated by distinct users, wherein the users consented to share pooled variant observations with other users; determining that a plurality of variant observations meet the inclusion criteria for a pool; and calculating one or more anonymized allele statistics from the pool.
Type:
Application
Filed:
August 15, 2014
Publication date:
February 18, 2016
Applicants:
QIAGEN Redwood City, Inc., QIAGEN GmbH
Inventors:
Douglas E. Bassett, JR., Daniel R. Richards, Peer M. Schatz
Abstract: Disclosed herein are system, method, and computer program product embodiments for aiding in the interpretation of variants observed in clinical sequencing data. An embodiment operates by receiving clinical trial enrollment criteria from a user, including but not limited to genetic targeting criteria; searching a knowledge base of patient test information received from a plurality of independent entities for patients that match the clinical trial enrollment criteria; and providing to the user search results for consented patients that match the clinical trial enrollment criteria.
Type:
Application
Filed:
June 30, 2014
Publication date:
December 31, 2015
Applicants:
QIAGEN Redwood City, Inc., QIAGEN GmbH
Inventors:
Douglas E. BASSETT, JR., Daniel R. Richards, Peer M. Schatz