Abstract: Methods and compositions for enriching a population of particles containing an analyte are disclosed. In one embodiment, enrichment beads are used that are larger in size than the beads used for amplification. A separation device is employed that can retain larger beads with bound amplified beads. The technique finds many uses, including enriching for beads with clonally amplified template, which can be used in a variety of assays, including nucleic acid sequencing.
Type:
Grant
Filed:
March 5, 2020
Date of Patent:
February 24, 2026
Assignee:
Qiagen Sciences, Inc.
Inventors:
Jerzy Olejnik, Steven Gordon, Martina Werner
Abstract: Disclosed is an isolated strain of a previously unknown Staphylococcus, Staphylococcus pseudolugdunensis. Also disclosed are the sequences of the S. pseudolugdunensis tuf gene and 16s rRNA and methods for distinguishing S. pseudolugdunensis from other staphylococcal species.
Type:
Application
Filed:
April 12, 2013
Publication date:
August 15, 2013
Applicants:
Qiagen Sciences, Inc., Vanderbilt University
Inventors:
Vanderbilt University, Qiagen Sciences, Inc.
Abstract: The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3? UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions.
Abstract: The present invention relates to sample presentation devices useful in performing analytical measurements. These devices have been configured to enable various aspects of liquid handling such as: retention, storage, transport, concentration, positioning, and transfer. Additionally, these devices can enhance the detection and characterization of analytes. The sample presentation devices of the present invention are comprised of one or more substrates having a plurality of zones of differing wettability. Methods of analyzing samples using the sample presentation device of the invention, as well as methods of making the sample presentation devices are disclosed.
Type:
Application
Filed:
May 24, 2010
Publication date:
March 24, 2011
Applicant:
Qiagen Sciences, Inc.
Inventors:
Christopher M. Belisle, John A. Walker, II, Sarah M. Ngola, Douglas P. Greiner, Mark J. Levy, Xiaoxia Zhao, Irene Y. Chen, Mark L. Stolowitz, Donald P. Paquin
Abstract: The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3? UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions.