Patents Assigned to Qingdao Huanghai Pharmaceutical Co., Ltd
  • DGAT1 inhibitor and preparation method and use thereof
    Patent number: 9809604
    Abstract: The present invention discloses a novel DGAT1 inhibitor, especially the compound of formula (I) or a pharmaceutically acceptable salt thereof, preparation and pharmaceutical composition thereof, as well as their uses in the preparation of a medicament for the prevention and treatment of Familial hyperchylomicronemia (FCS), obesity, hyperlipoproteinemia or hypertriglyceridemia.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: November 7, 2017
    Assignees: Qingdao Huanghai Pharmaceutical Co., Ltd., Medshine Discovery Inc.
    Inventors: Chengde Wu, Zhiliu Zhang, Tao Yu
  • 2-methyl-5-imino-benzo[D][1 ,3]oxazin[5-B]pyrazole compound, preparation and use thereof
    Patent number: 7973036
    Abstract: The present invention disclosed compound 2-methyl-5-imino-benzo[d][1,3]oxazin[5-b]pyrazole and preparation method and uses thereof. The compound 2-methyl-5-imino-benzo[d][1,3]oxazin[5-b]pyrazole of the present invention has the following structure of formula (II), wherein the compound or pharmaceutically acceptable salts thereof can be used for preparing the drugs for treatment or prevention of cardiovascular diseases.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: July 5, 2011
    Assignees: Qingdao Huanghai Pharmaceutical Co., Ltd, Nanjing Zhongrui Medicine Co., Ltd.
    Inventors: Guoqiang Su, Yicai Gao, Guirong Sun, Liming Wu, Yu Ren
  • 2-Methyl-5-Imino-Benzo[D][1,3]Oxazin[5-B]Pyrazole Compound, Preparation and Use Thereof
    Publication number: 20110118247
    Abstract: The present invention disclosed compound 2-methyl-5-imino-benzo[d][1,3]oxazin[5-b]pyrazole and preparation method and uses thereof. The compound 2-methyl-5-imino-benzo[d][1,3]oxazin[5-b]pyrazole of the present invention has the following structure of formula (II), wherein the compound or pharmaceutically acceptable salts thereof can be used for preparing the drugs for treatment or prevention of cardiovascular diseases.
    Type: Application
    Filed: March 20, 2009
    Publication date: May 19, 2011
    Applicants: QINGDAO HUANGHAI PHARMACEUTICAL CO., LTD., NANJING ZHONGRUI MEDICINE CO., LTD.
    Inventors: Guoqiang Su, Yicai Gao, Guirong Sun, Liming Wu, Yu Ren