Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).
Type:
Grant
Filed:
October 10, 2018
Date of Patent:
March 29, 2022
Assignee:
Qpex Biopharma, Inc.
Inventors:
Scott J. Hecker, Serge Henri Boyer, Hubertus J. A. Dielemans, Angela Gonzalez de Castro, Andreas H. M. de Vries, Laurent Lefort
Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).
Type:
Grant
Filed:
February 18, 2020
Date of Patent:
November 23, 2021
Assignee:
Qpex Biopharma, Inc.
Inventors:
Scott J. Hecker, Raja K. Reddy, Tomasz Glinka, Olga Rodny
Abstract: Disclosed herein are antimicrobial compounds, compositions, pharmaceutical compositions, and the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
Type:
Grant
Filed:
November 13, 2015
Date of Patent:
May 26, 2020
Assignee:
QPEX BIOPHARMA, INC.
Inventors:
Scott Hecker, Raja K. Reddy, Tomasz Glinka
Abstract: Disclosed herein are antimicrobial compounds having the structure of the formula III? pharmaceutical compositions, the use and preparation thereof. The compounds are of the class of boronic acid derivatives, useful for antimicrobial treatment.
Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).
Type:
Grant
Filed:
April 8, 2019
Date of Patent:
February 25, 2020
Assignee:
Qpex Biopharma, Inc.
Inventors:
Scott J. Hecker, Raja K. Reddy, Tomasz Glinka, Olga Rodny
Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, ?-lactamase inhibitors (BLIs).
Type:
Grant
Filed:
June 28, 2017
Date of Patent:
May 21, 2019
Assignee:
Qpex Biopharma, Inc.
Inventors:
Scott J. Hecker, Raja K. Reddy, Tomasz Glinka, Olga Rodny
Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents.
Type:
Grant
Filed:
June 29, 2015
Date of Patent:
February 19, 2019
Assignee:
QPEX BIOPHARMA, INC.
Inventors:
Raja K. Reddy, Tomasz Glinka, Maxim Totrov, Scott Hecker, Olga Rodny