Abstract: The present disclosure relates to cybersecurity architectures and systems for assessing and quantifying security threats and risks associated with machine-readable codes, such as quick response codes, barcodes, data matrix codes, and other types of codes. A security application comprises a multi-context threat assessment system configured to analyze a broad spectrum of risk assessment attributes across multiple contexts. These contexts relate to the machine-readable code itself, target network resources identified by the code, entities affiliated with the code, end-users interacting with the code, and enterprise systems policies. The system can evaluate various risk assessment attributes for each of these contexts to more accurately quantify potential security risks associated with the machine-readable codes.