Abstract: Methods, systems and apparatus for the analysis of biological samples. Biological sample held in sample plates may be processed by a PCR machine. PCR curves are generated for each biological sample and analyzed by one or more machine learning models. The PCR curves are assigned a confidence level and classified based on the analysis and the confidence level. PCR curve with a confidence level below a predetermined threshold may be flagged for analysis by a lab director. PCR curves flagged for manual analysis may be displayed on an analysis interface. The lab director may view, analyze and classify the flagged PCR curves through interaction with the analysis interface.
Abstract: Methods, systems and apparatus for the tracking and managing of biological samples. A provider may check-in or register a patient at a provider facility. A sample tube may be registered to the patient, and a biological sample may be collected. The provider aggregates a plurality of sample tubes into cells of a rack. The provider then captures an image of the rack. A computer vision operation may be performed to isolate and identify a QR code affixed to the lid of each sample tube. The identified sample tubes are registered to the rack in which they are held, and the rack transferred to a destination lab. The same computer vision operation may be performed upon receipt of the rack. The samples may then be transferred to a sample plate. The samples are transferred from a cell in the rack to a corresponding well in the sample plate.
Abstract: The present invention provides methods, compositions, reaction mixtures, and kits for detecting cancer biomarkers in a bodily fluid from a subject. Also provided are methods for selecting cancer biomarkers for use in detecting one or more types of cancer in a subject.