Patents Assigned to Quantitative Informational Knockout Technology
  • Transplacental delivery of oligonucleotides
    Patent number: 6576218
    Abstract: This invention provides synthetic oligonucleotides that are useful for transplacental delivery, the oligonucleotides being DNA or RNA or both, preferably between 12-35 nucleotides in length, having a stabilized and charged backbone and at least one chemically modified base or sugar moiety, wherein the modified base or sugar moiety facilitates transplacental delivery.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: June 10, 2003
    Assignee: Quantitative Informational Knockout Technology
    Inventors: Peter C. Roberts, Samuel E. Driver