Patents Assigned to Queen's University at Kingston
  • Patent number: 9757817
    Abstract: A method, apparatus, and system are provided to monitor and characterize the dynamics of a phase change region (PCR) created during laser welding, specifically keyhole welding, and other material modification processes, using low-coherence interferometry. By directing a measurement beam to multiple locations within and overlapping with the PCR, the system, apparatus, and method are used to determine, in real time, spatial and temporal characteristics of the weld such as keyhole depth, length, width, shape and whether the keyhole is unstable, closes or collapses. This information is important in determining the quality and material properties of a completed finished weld. It can also be used with feedback to modify the material modification process in real time.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 12, 2017
    Assignee: Queen's University at Kingston
    Inventor: Paul J. L. Webster
  • Patent number: 9743912
    Abstract: An ultrasound calibration phantom comprises a portion including at least one fiducial structure having a selected geometric arrangement; a portion adapted for mechanical coupling of the ultrasound calibration phantom to a transrectal ultrasound (TRUS) stepper; and a guide for at least one surgical instrument, the guide being mechanically coupled to the fiducial structure and/or to the TRUS stepper at a selected pose relative to the fiducial structure. A calibration method uses the calibration phantom and provides automatic, intraoperative calibration of ultrasound imaging systems. The invention is useful in ultrasound-guided clinical procedures.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: August 29, 2017
    Assignee: QUEEN'S UNIVERSITY AT KINGSTON
    Inventors: Gabor Fichtinger, Purang Abolmaesumi, Clif E. Burdette, Thomas Kuiran Chen, Andras Lasso, Tamas Heffter
  • Patent number: 9738606
    Abstract: A compound of Formula I, Formula IA, Formula IB, or Formula II, or an acid or base addition salt thereof, and use of these compounds as antioxidants. In one embodiment, a compound of Formula II, wherein each of X, Y, and Z are independently a carbon or nitrogen atom; R1 and R2 are each independently a hydrogen or an electron donating group, but are not both hydrogen, and wherein R1, and R2 are each bonded to a carbon atom in their own respective aryl ring.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: August 22, 2017
    Assignees: Queen's University at Kingston, Alma Mater Studiorum—Universita Di Bologna
    Inventors: Derek A. Pratt, Jason J. Hanthorn, Luca Valgimigli
  • Patent number: 9701086
    Abstract: Described is a substantially spherical biomass pellet, comprising compressed particulate biomass including one or more of ligno-cellulosic material, recycling waste, and dewatered municipal solid waste, useful as a fuel. Also described are methods for producing such pellets using one or more of untorrefied biomass and torrefied biomass, and apparatus for producing such biomass pellets.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: July 11, 2017
    Assignee: Queen's University at Kingston
    Inventors: William Andrew Duncan, Andrew Pollard, M. Hachimi Fellouah
  • Patent number: 9693878
    Abstract: Provided is a preoperatively designed guidance tool for intraoperative use during acetabular cup replacement surgery, comprising: a patient-specific template having at least one surface that registers with a selected surface of the patient's acetabulum; and a guide portion that provides an orientation or a position and orientation of an acetabular cup according to a preoperatively planned orientation or position and orientation. The guidance tool may further comprise a verification tool that cooperates with the guide portion and includes at least one mating surface that registers with a selected surface of the patient's anatomy, wherein correct positioning of the verification tool on the patient's anatomy confirms correct orientation of the patient-specific template in the patient's acetabulum.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: July 4, 2017
    Assignee: Queen's University at Kingston
    Inventors: Manuela Kunz, John F. Rudan
  • Patent number: 9629939
    Abstract: Provided is a foam material, comprising a plurality of substantially collagenous beads, wherein the foam material is a bead foam, and wherein adjacent collagenous beads are fused together by a network of collagen fibers. Also provided are methods for preparation of foam materials comprising a plurality of substantially collagenous beads. The foam materials may be used in applications such as bioscaffolds for wound healing, soft tissue regeneration and augmentation, for localized cell delivery, or as cell culture substrates for research. The foam materials include natural collagen fibrils that provide a stable scaffold and enhance integration of the implanted scaffold and regeneration of cells and tissue.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: April 25, 2017
    Assignee: Queen's University at Kingston
    Inventors: Lauren E. Flynn, Claire Yu
  • Patent number: 9607690
    Abstract: Provided are modified one-hot (MOH) constructions for WOM codes with low encoding and decoding complexity, that achieve high sum-rates. Features include maximizing writing of data information values for successive rewrites, all-zero and all-one cell state vectors that represent a unique data information value that can be written for many generations, a very high number of writes, and does not sacrifice capacity. One embodiment comprises ordered or unordered MOH code that approaches the upper-bound for large n wits. According to the embodiments, before an erasure is needed, the majority of the wits are encoded, which provides level wearing and maximizes life of cells.
    Type: Grant
    Filed: January 18, 2016
    Date of Patent: March 28, 2017
    Assignee: Queen's University at Kingston
    Inventors: Jay Hua, Shahram Yousefi
  • Publication number: 20170079095
    Abstract: Described herein are methods and circuits for improving the performance of an AC to DC power supply. The methods and circuits achieve high power factor (PF) at the AC side and at the same time, reduce or substantially eliminate ripple in the DC output power. The methods and circuits provide an isolated topology including primary side voltage and current sensing and primary side ripple cancellation control. The methods and circuits may be used in any application where high power factor and/or low output ripple are required. In particular, the methods and circuits may be used in DC lighting applications, such as in light emitting diode (LED) lighting, wherein suppression of low frequency ripple in the output power eliminates visible flickering.
    Type: Application
    Filed: March 13, 2015
    Publication date: March 16, 2017
    Applicant: Queen's University at Kingston
    Inventors: Peng Fang, Yan-Fei Liu
  • Publication number: 20170049753
    Abstract: Methods and compositions for enhancing fertility and/or inhibiting pregnancy failure, restoring glucose tolerance and/or preventing glucose intolerance and/or maintaining glucose homeostasis and/or increasing insulin sensitivity and/or preventing weight gain and/or inducing or enhancing weight loss, treating dyslipidemia, treating hypertestosteronism or hyperandrogenism, and/or treating type 2 diabetes in an individual in need thereof are provided.
    Type: Application
    Filed: August 29, 2016
    Publication date: February 23, 2017
    Applicant: Queens University at Kingston
    Inventors: Ahmad J.H. Albaghdadi, Frederick W.K. Kan
  • Patent number: 9457428
    Abstract: Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser or welding applications. An imaging optical source that produces imaging light. A feedback controller controls at least one processing parameter of the material modification process based on an interferometry output generated using the imaging light. A method of processing interferograms is provided based on homodyne filtering. A method of generating a record of a material modification process using an interferometry output is provided.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: October 4, 2016
    Assignee: Queen's University at Kingston
    Inventors: Paul J. L. Webster, James M. Fraser, Victor X. D. Yang
  • Patent number: 9427433
    Abstract: Methods and compositions for enhancing fertility and/or inhibiting pregnancy failure, restoring glucose tolerance and/or preventing glucose intolerance and/or maintaining glucose homeostasis and/or inducing or enhancing weight loss, treating dyslipidemia, treating hypertestosteronism or hyperandrogenism, and/or treating type 2 diabetes in an individual in need thereof are provided. These involve compositions that inhibit expression of interferon-gamma (IFN-?) or a downstream IFN-?-stimulated gene, which is preferably a macrolide immunosuppressant compound.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: August 30, 2016
    Assignee: Queen's University at Kingston
    Inventors: Ahmad J. H. Albaghdadi, Frederick W. K. Kan
  • Publication number: 20160244548
    Abstract: The present application provides a composite material that comprises a solid and solid-supported non-polymeric switchable moiety, wherein the switchable moiety comprises a functional group that is switchable between a first form and a second form, said first form being neutral and hydrophobic, and said second form being ionized and hydrophilic. The composite material converts to, or is maintained in, said second form when the switchable moiety is exposed to CO2 at amounts sufficient to maintain the ionized form. The composite material converts to, or is maintained in, said first form when CO2 is removed or reduced to an amount insufficient to maintain the ionized form. CO2 is removed or reduced by exposing the composite material to heat and/or a flushing inert gas such as N2, Ar, or air. Envisioned uses of these composite materials includes removing water from non-aqueous solvents, removing water vapour from gaseous mixtures, and cleaning industrial reaction vessels and/or pipelines.
    Type: Application
    Filed: September 18, 2014
    Publication date: August 25, 2016
    Applicants: Queen's University at Kingston, GreenCentre Canada
    Inventors: Kyle J. Boniface, Timothy James Clark, Michael F. Cunningham, Philip G. Jessop, Brian Ernest Mariampillai, Sean M. Mercer, Rui Resendes, Tobias Robert
  • Patent number: 9419510
    Abstract: Provided are circuits and methods for use with a power supply that provides a main output including a main DC voltage having a first AC voltage ripple, or a main DC current having a first AC current ripple. A ripple cancellation converter provides a second AC voltage ripple connected in series with the main output, such that the first AC voltage ripple is substantially cancelled; or a second AC current ripple connected in parallel with the main output, such that the first AC current ripple is substantially cancelled. As a result, substantially ripple-free DC output power is provided.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: August 16, 2016
    Assignee: Queen's University at Kingston
    Inventor: Yan-Fei Liu
  • Patent number: 9407125
    Abstract: An apparatus and method for generating electrical power from a user comprises a motion capture apparatus that captures at least a portion of motion of a pair of limbs of the user; a motion integrator mechanically coupled to the motion capture apparatus such that captured motion of the pair of limbs is transferred to the motion integrator, and the motion integrator produces an output motion; an adaptive controller, and an electrical generator mechanically coupled to the output motion of the motion integrator; wherein the electrical generator generates electrical power from the output motion of the motion integrator. The apparatus may be adapted to be carried on the user's back. In one embodiment the apparatus is incorporated into a backpack.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: August 2, 2016
    Assignee: Queen's University at Kingston
    Inventors: Michael Y. Shepertycky, Qingguo Li, Yan-Fei Liu
  • Patent number: 9351744
    Abstract: Presented is a preoperatively designed guidance tool for intraoperative use during bone or joint surgery wherein the guidance tool is specific to the anatomy of the patient being treated. The guidance tool comprises a body portion, a mating surface provided on the body portion for positioning the guidance tool on a corresponding registration surface of a patient's anatomy. The guidance tool further comprises at least one guide mechanism provided on the body portion for guiding a medical instrument at one or more preoperatively defined trajectories relative to a patient's anatomy. In the event of misalignment, the at least one guide mechanism is adjustable to alter the one or more preoperatively defined trajectories if necessary during intraoperative use. Also presented is a preoperative process for designing the guidance tool.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: May 31, 2016
    Assignee: Queen's University at Kingston
    Inventors: Manuela Kunz, John F. Rudan
  • Patent number: 9282944
    Abstract: This invention provides a method for estimating C-arm fluoroscope pose. The method involves introducing a coordinate system into a C-arm image, and applying intensity-based 2D/3D registration without segmentation to the coordinate system C-arm image and an image or known model of the coordinate system, wherein the intensity-based 2D/3D registration yields the C-arm pose. The coordinate system may be provided by introducing one or more markers or a fiducial into an image.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: March 15, 2016
    Assignee: QUEEN'S UNIVERSITY AT KINGSTON
    Inventors: Pascal Fallavollita, Gabor Fichtinger, Purang Abolmaesumi, E. Clif Burdette
  • Publication number: 20160051726
    Abstract: Provided is a foam material, comprising a plurality of substantially collagenous beads, wherein the foam material is a bead foam, and wherein adjacent collagenous beads are fused together by a network of collagen fibres. Also provided are methods for preparation of foam materials comprising a plurality of substantially collagenous beads. The foam materials may be used in applications such as bioscaffolds for wound healing, soft tissue regeneration and augmentation, for localized cell delivery, or as cell culture substrates for research. The foam materials include natural collagen fibrils that provide a stable scaffold and enhance integration of the implanted scaffold and regeneration of cells and tissue.
    Type: Application
    Filed: May 16, 2013
    Publication date: February 25, 2016
    Applicant: QUEEN'S UNIVERSITY AT KINGSTON
    Inventors: Lauren E. Flynn, Claire Yu
  • Patent number: 9097672
    Abstract: A system for detecting presence of an organism having an enzyme in a sample, comprising: a cartridge for containing the sample and a substrate such that the enzyme can react with the substrate to produce a biological molecule; a partitioning element mounted in a recess in a base of the cartridge, the partitioning element allowing partitioning of the biological molecule thereinto; a light source for irradiating the biological molecule partitioned into the partitioning element; and, a detector for detecting fluorescence of the biological molecule partitioned into the partitioning element, the detected fluorescence being indicative of presence of the organism in the sample; wherein the light source is in a raised cartridge mount of the system that mates with the recess in the base of the cartridge.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: August 4, 2015
    Assignees: QUEENS'S UNIVERSITY AT KINGSTON, PATHOGEN DETECTION SYSTEMS, INC.
    Inventors: R. Stephen Brown, Eric Marcotte, Doug Wilton, Peter Gallant, David Dolphin, Lee Underwood
  • Publication number: 20150197817
    Abstract: Methods, probe sets, kits, and compositions for gene deletion assays are disclosed. In some embodiments, the methods relate to preparing probes for a deletion assay, performing a deletion assay, or optimizing a deletion assay. In some embodiments, the methods and probe sets can provide reduced artifactual deletion frequency, for example, when analyzing samples subject to truncation artifacts. In some embodiments, the methods and probe sets can distinguish between small and large deletions.
    Type: Application
    Filed: January 6, 2015
    Publication date: July 16, 2015
    Applicants: Kingston General Hospital, Queen's University at Kingston
    Inventors: Jeremy A. Squire, Maisa Yoshimoto
  • Publication number: 20150190772
    Abstract: The present application provides a micellar composition having switchable viscosity.
    Type: Application
    Filed: August 2, 2013
    Publication date: July 9, 2015
    Applicant: QUEEN'S UNIVERSITY AT KINGSTON
    Inventors: Philip G. Jessop, Michael F. Cunningham, Xin Su