Patents Assigned to Questcor Pharmaceuticals, Inc.
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Patent number: 9550822Abstract: Provided herein are methods for prophylactic treatment of renal disorders comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual suspected of having, predisposed to, or at risk of developing a renal disorder.Type: GrantFiled: June 24, 2014Date of Patent: January 24, 2017Assignees: QUESTCOR PHARMACEUTICALS, INC., RHODE ISLAND HOSPITALInventors: Steve Cartt, Rujun Gong
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Publication number: 20140322226Abstract: Provided herein are methods of treatment of acute respiratory distress syndrome comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual in need thereofType: ApplicationFiled: March 14, 2014Publication date: October 30, 2014Applicant: QUESTCOR PHARMACEUTICALS, INC.Inventors: James KNIGHT, Steve CARTT, David YOUNG, Patrice BECKER
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Publication number: 20140294923Abstract: Provided herein are methods of treatment of migraine headaches comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual in need thereof.Type: ApplicationFiled: February 19, 2014Publication date: October 2, 2014Applicant: Questcor Pharmaceuticals, Inc.Inventors: Steve CARTT, James KNIGHT
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Patent number: 8796416Abstract: Provided herein are methods for prophylactic treatment of renal disorders comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual suspected of having, predisposed to, or at risk of developing a renal disorder.Type: GrantFiled: October 25, 2011Date of Patent: August 5, 2014Assignee: Questcor Pharmaceuticals, IncInventors: Steve Cartt, Rujun Gong
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Publication number: 20130259875Abstract: Provided herein are methods of treatment of Amyotrophic Lateral Sclerosis comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual in need thereof.Type: ApplicationFiled: May 10, 2011Publication date: October 3, 2013Applicant: QUESTCOR PHARMACEUTICALS, INC.Inventor: Kathleen C. Somera-Molina
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Publication number: 20100016294Abstract: Disclosed herein is a method for treating a patient with Quazepam that reduces the risk of an adverse interaction between the Quazepam and drug that is a substrate of the cytochrome P450 enzyme isoform 2B6 (CYP2B6 substrate drug), e.g., Bupropion. The method includes determining if the patient to be treated with Quazepam is being treated with a CYP2B6 substrate drug, and prescribing or treating the patient with Quazepam based on the determination.Type: ApplicationFiled: September 25, 2009Publication date: January 21, 2010Applicant: QUESTCOR PHARMACEUTICALS, INC.Inventor: Steve Cartt
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Patent number: 7608616Abstract: Disclosed herein is a method for treating a patient with Quazepam that reduces the risk of an adverse interaction between the Quazepam and drug that is a substrate of the cytochrome P450 enzyme isoform 2B6 (CYP2B6 substrate drug), e.g., Bupropion. The method includes determining if the patient to be treated with Quazepam is being treated with a CYP2B6 substrate drug, and prescribing or treating the patient with Quazepam based on the determination.Type: GrantFiled: June 3, 2008Date of Patent: October 27, 2009Assignee: Questcor Pharmaceuticals, Inc.Inventor: Steve Cartt
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Publication number: 20080279784Abstract: Particulate formulations of benzodiazepines, such as diazepam, are used for nasal administration of diazepine drugs to patients. Multimodal particulate formulations of benzodiazepines and methods for their use, e.g. by nasal administration for the treatment of seizure, are also provided.Type: ApplicationFiled: May 7, 2008Publication date: November 13, 2008Applicant: QUESTCOR PHARMACEUTICALS, INC.Inventors: Steve Cartt, David Medeiros
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Publication number: 20080021074Abstract: Pharmaceutical compositions comprising at least one alpha2-adrenergic agonist or baclofen and at least one alpha1-adrenergic agonist are disclosed. Pharmaceutical compositions comprising tizanidine and modafinil are disclosed. Methods for reducing somnolence, sleepiness, lethargy, dizziness, drowsiness, somnolence, tiredness, lightheadedness, increased weakness, confusion, unsteadiness, clumsiness, or a combination of the symptoms thereof in a human patient; treating pain; and attenuating muscle spasticity, using pharmaceutical compositions comprising at least one alpha2-adrenergic agonist or baclofen and at least one alpha1-adrenergic agonist are disclosed.Type: ApplicationFiled: June 29, 2007Publication date: January 24, 2008Applicant: QUESTCOR PHARMACEUTICALS, INC.Inventor: Steve Cartt
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Patent number: 6770262Abstract: The present invention is directed to a method for the treatment of gastroparesis by the use of metoclopramide nasal formulation.Type: GrantFiled: March 29, 2001Date of Patent: August 3, 2004Assignee: Questcor Pharmaceuticals, Inc.Inventors: Laura S. Lehman, David Tierney, Anastassios D. Retzios, Michael Petrone, David Young, Carol B. Trapnell, Ruth Oliver
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Patent number: 6410715Abstract: Method for screening for a non-hormone agent potentially useful to treat a hormone disorder The method involves contacting a potential agent with a system containing a cellular component and a translation factor. The component and factor interact with one another in an intact normal cell in a manner responsive to the hormone to cause a modulation of translation in the cell. The method involves determining whether the agent causes a modulation of translation by the component and the factor analogous to that which occurs in intact cells in response to the hormone.Type: GrantFiled: June 14, 2000Date of Patent: June 25, 2002Assignees: Questcor Pharmaceuticals, Inc., Mc Gill UniversityInventors: Nahum Sonenberg, Arnim Pause, Joe B. Harford, Vincent J. Miles
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Patent number: 6312707Abstract: Fructose-1,6-diphosphate (FDP) has been shown, in double-blinded controlled clinical trials on patients with sickle cell anemia, to substantially reduce the pain suffered by such patients during the recurrent ischemic crises that are caused by red blood cell sickling. Tests on patients who have been hospitalized for such crises demonstrated that when they received an intravenous injection of FDP, they reported substantially lower pain levels during their hospital stays than control groups that received identical treatment without any FDP. Apparently, FDP has never previously been used or even tested in human clinical trials, to treat sickle cell anemia. In addition, FDP has never previously been reported to have any analgesic (pain-reducing) activity.Type: GrantFiled: June 12, 2000Date of Patent: November 6, 2001Assignee: Questcor Pharmaceuticals, Inc.Inventors: Angel K. Markov, Anthony W. Fox, Paul J. Marangos
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Patent number: 6251898Abstract: Newly-created fluorenone drugs can be used to prevent, treat, or otherwise reduce damage to a brain or spinal cord following a medical crisis. These new drugs are markedly improved analogs of previously-known fluorenone compounds that were never commercialized or developed into medically useful treatments. The new analogs have the following structure: where X is a lower alkyl, substituted alkyl, or cycloalkyl group, R is selected from certain types of ether, ester, or amide groups, and Y1 and Y2 are halogen, hydrogen, or methyl. These new compounds can penetrate a blood-brain barrier and potently inhibit the unwanted release of excitotoxic neurotransmitters by astrocyte cells following an injury or insult to the brain or spinal cord. As an illustration, some of these new analogs were more than 30 times more potent than the previously known best compound in reducing aspartate release by stressed astrocytes.Type: GrantFiled: August 24, 1999Date of Patent: June 26, 2001Assignee: Questcor Pharmaceuticals, Inc.Inventors: Edward J. Cragoe, Jr., Paul J. Marangos, Torsten R. Weimann