Patents Assigned to Quiral Quimica Do Brasil S.A.
  • Stable pharmaceutical compositions with docetaxel
    Patent number: 8304450
    Abstract: The invention relates to pharmaceutical compositions comprising anhydrous(2R,3S)4-acetoxy-2-a-benzoyloxy-5?-20-epoxy-1,7-?-10-?-tri-hydroxy-9-oxo-tax-11-en-13?-il 3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I)(docetaxel) and 4-acetoxy-2-?-benzoyloxy-5-?-20-epoxy-1,7?-10-?-tri-hydroxy-9-oxo-tax-11-en-13?-il (2R,3S)3-benzoylamino-2-hydroxy-3-phenylpropionate (II) (paclitaxel), methods for treating neoplastic tumors using anhydrous docetaxel and paclitaxel, and a process for the preparation of the anhydrous docetaxel and paclitaxel.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: November 6, 2012
    Assignees: Quiral Quimica Do Brasil S.A., Biorganica Ltda.
    Inventors: Marco Antônio Santini, Antônio Machado, Aurélio Maranduba, Eneida Guimarães, Marcio Santiago Junior, Maria Silva
  • PHARMACEUTICAL COMPOSITIONS CONTAINING DOCETAXEL AND A DEGRADATION INHIBITOR AND A PROCESS FOR OBTAINING THE SAME
    Publication number: 20090221688
    Abstract: Pharmaceutical compositions containing polysorbate 80, anhydrous docetaxel (I) or its trihydrate and an organic acid with a pKa between 2.5-4.5 employed as a degradation inhibitor.
    Type: Application
    Filed: February 9, 2006
    Publication date: September 3, 2009
    Applicants: Quiral Quimica DO Brasil S.A., Biorganica Ltda.
    Inventors: Antonio Machado, Aurelio Maranduba, Eneida Guimaraes, Livia Machado, Marcio Santiago, JR., Maria Silva