Abstract: The present application is drawn to a system and method, as well as method for manufacture of a device and system for determining the position and orientation of at least one magnetic field sensor comprising: a rigid structure comprising an array of at least five electromagnetic coils; at least one wire that connects to and powers the electromagnetic coils; wherein the placement and orientation of the electromagnetic coils on the rigid structure are predetermined; wherein the electromagnetic coils, each having a predefined magnetic moment per unit current, are constructed with a printed circuit board (PCB) comprising at least one conductive layer; and wherein the system is configured such that a stray magnetic field emanating from the at least one, as measured at the location of the at least one magnetic field sensor, generates substantially lower magnetic field intensity than that produced by each of the at least five electromagnetic coils.

Abstract: A wearable and customizable multi-shell MEG helmet comprising an inner shell and outer shell, wherein the inner shell interior surface is customized to conform to the patient's head shape so that the helmet assembly moves in unison with the patient's head movement and sensor locations are controlled and remain fixed relative to the brain. This invention improves data quality and user comfort since head movements may be permitted and their effects on data integrity is minimized. The outer shell is generic and may fit over any customized inner shell. The outer shell holds a group of sensors, which may be, but not limited to, optically pumped magnetometers. This generic outer shell may mate with the inner shell, allowing sensors to be easily pushed into the inner shell to be in closer proximity to the patient's head.

Abstract: A calibration system and method is described to continuously measure and adjust several parameters of a magnetic imaging array. One or more non-target magnetic field source(s) are used to generate a well-defined and distinguishable spatial magnetic field distribution. The magnetic imaging array is used to measure the strength of the non-target magnetic fields and the information is used to calibrate several parameters of the array, such as, but not limited to, effective magnetometer positions and orientations, gains and their frequency dependence, bandwidth, and linearity. The calibration can happen continuously or periodically, while the imaging array is operating to create magnetic field images, if the modulation frequencies for calibration are outside the frequency window of interest.

Abstract: A system and method to measure a magnetic gradient field with an optically-pumped magnetometer is described. Atoms are spin polarized at two locations. Larmor frequencies are, induced and the spin frequency is detected. The frequencies are proportional to the total magnetic field at the locations of the atoms. The magnetic field gradient is extracted from the beat frequency of the two Larmor frequencies.

Abstract: A zero-field paramagnetic resonance magnetometer (ZF-PRM) system and method for quickly and efficiently finding and optimizing the zero-field (ZF) resonance is described. In this system and method a magnetic coil is used to apply a magnetic bias field in the direction of the pump beam to artificially broaden the width and maximize the strength of the ZF resonance. By making the ZF resonance easy to detect, the ZF resonance may be found quickly found without the use of additional components and complex algorithms. Once the ZF resonance is found, a compensating magnetic field can be applied to null the magnetic field in the vicinity of the vapor cell in the ZF-PRM, thereby initializing it for operation.

Abstract: A zero-field paramagnetic resonance magnetometer (ZF-PRM) system and method for quickly and efficiently finding and optimizing the zero-field (ZF) resonance is described. In this system and method a magnetic coil is used to apply a magnetic bias field in the direction of the pump beam to artificially broaden the width and maximize the strength of the ZF resonance. By making the ZF resonance easy to detect, the ZF resonance may be found quickly found without the use of additional components and complex algorithms. Once the ZF resonance is found, a compensating magnetic field can be applied to null the magnetic field in the vicinity of the vapor cell in the ZF-PRM, thereby initializing it for operation.

Abstract: A zero-field paramagnetic resonance magnetometer (ZF-PRM) system and method for quickly and efficiently finding and optimizing the zero-field (ZF) resonance is described. In this system and method a magnetic coil is used to apply a magnetic bias field in the direction of the pump beam to artificially broaden the width and maximize the strength of the ZF resonance. By making the ZF resonance easy to detect, the ZF resonance may be found quickly found without the use of additional components and complex algorithms. Once the ZF resonance is found, a compensating magnetic field can be applied to null the magnetic field in the vicinity of the vapor cell in the ZF-PRM, thereby initializing it for operation.