Abstract: Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.
Type:
Application
Filed:
September 14, 2023
Publication date:
March 7, 2024
Applicant:
Qwixel Therapeutics LLC
Inventors:
David STOVER, Sherie MORRISON, Alex VASUTHASAWAT, Kham TRINH, George AYOUB
Abstract: Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.
Type:
Grant
Filed:
September 2, 2021
Date of Patent:
October 24, 2023
Assignee:
Qwixel Therapeutics LLC
Inventors:
David Stover, Sherie Morrison, Alex Vasuthasawat, Kham Trinh, George Ayoub
Abstract: Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.
Type:
Application
Filed:
September 2, 2021
Publication date:
February 24, 2022
Applicant:
Qwixel Therapeutics LLC
Inventors:
David STOVER, Sherie MORRISON, Alex VASUTHASAWAT, Kham TRINH, George AYOUB
Abstract: Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.
Type:
Grant
Filed:
April 15, 2020
Date of Patent:
October 5, 2021
Assignee:
Qwixel Therapeutics LLC
Inventors:
David Stover, Sherie Morrison, Alex Vasuthasawat, Kham Trinh, George Ayoub