Abstract: A method of treating skin including the application of a treatment gas to a surface of the skin and simultaneous neuro-muscular stimulation of the skin. The increased blood flow resulting from the neuro-muscular stimulation improves the effectiveness of the treatment gas. A medicine may be applied to the skin along with the treatment gas and the temperature of the treatment gas may be controlled to achieve a desired therapy. In one embodiment, a wound is treated by stimulating neuro-muscular activity near the wound while simultaneously applying an antibiotic and oxygen gas to the wound at a first warm temperature and then at a second cool temperature. The treatment gas applicator used to deliver the oxygen to the wound may further be used to provide repeatable measurements of the size of the wound over time. Other beneficial skin effects, such as hair growth and age retardation, may be achieved by applying specific treatment gases and medicines simultaneously with neuro-muscular stimulation.