Abstract: An algorithm is disclosed that detects and analyzes possible lesions that are left in contact with a structural boundary. A morphological closing with a structuring element is performed along the boundary to detect lesions within the threshold of the structuring element. A deformable surface-based analysis is performed on distinctive surfaces of the structure for the identification of lesions. The integrated use of a deformable surface model and chamfer distance potential enables explicit representation of regularized, or smoothed, surfaces from which lesion candidates may be detected.