Patents Assigned to R2 Technology
  • Patent number: 12133669
    Abstract: The present is directed to improved systems, methods, and devices for providing skin cooling treatment. The skin cooling treatment system can include a mechanical arm and a cryospray applicator coupled to a distal end of the mechanical arm. The skin cooling treatment system can include a processor that can receive imagery of a portion of skin of a patient for receiving a skin cooling treatment and automatically identify boundaries from the received imagery to designate portions of the skin of the patient for receiving the skin cooling treatment. The processor can determine an instantaneous treatment footprint and can generate a treatment path based on the treatment footprint. The processor can control the cryospray applicator to deliver the skin cooling treatment to the skin according to the treatment path.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: November 5, 2024
    Assignee: R2 Technologies, Inc.
    Inventors: Jesse Rosen, Erica Elford, Dylan McReynolds, Erik Stauber
  • Patent number: 12004797
    Abstract: Embodiments of the present invention generally relate to methods, devices, and systems for reducing a pigmentation of a skin of a patient. In some embodiments, freezing of the skin may be desirable to effect the hypopigmentation of the skin of the patient. Generally, embodiments may limit supercooling (or promote freezing) of the skin of the patient during a cooling treatment. In some embodiments, coupling fluids are provided to reduce a thermal contact resistance between a cooling treatment probe and the skin of the patient to improve cooling treatment. Optionally, a fluid carrier may be provided to help retain the coupling fluid at the treatment site. In some embodiments, the coupling fluid may include ice nucleating agents to promote ice crystal formation in the coupling fluid during cooling treatment. The ice crystal formation in the coupling fluid may progress into the skin to limit supercooling of the skin during treatment.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: June 11, 2024
    Assignee: R2 Technologies, Inc.
    Inventors: Jesse Rosen, Kevin Springer, Kristine Tatsutani, Michael O'Neil
  • Patent number: 11974816
    Abstract: The present is directed to improved systems and methods for skin cooling treatments. A skin cooling treatment system can include a mechanical arm that can have a proximal end and an distal end. The system can include a processor that can control the mechanical arm, and a cryospray applicator. The cryospray applicator can be coupled to the distal end of the mechanical arm and can be moveable by the mechanical arm to deliver a spray of cryogen to a portion of an area of skin tissue for treatment. The cryospray applicator can include an array of orifices through which the cryogen can be sprayed.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: May 7, 2024
    Assignee: R2 Technologies, Inc.
    Inventors: Jesse Rosen, Erica Elford, Dylan McReynolds, Erik Stauber
  • Patent number: 11786286
    Abstract: The present invention is directed to improved systems, devices, and methods for delivery of a cryogen to the skin of a patient for skin treatment. A cryospray device configured to deliver a cryogen to a patient's skin can include an applicator, a supply channel, and a nozzle assembly. The applicator can include a head portion, and the supply channel can extend through at least a portion of the head portion. The nozzle assembly can be coupled to the head portion and can be fluidly coupled to the supply channel. The nozzle assembly can include a linear array of orifices that are configured to direct a planar spray of the cryogen to cool an area of a skin tissue of the patient in a linear cooling treatment.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: October 17, 2023
    Assignee: R2 Technologies, Inc.
    Inventors: Jesse Rosen, Erik Stauber, Steven Harrington, Ryan Richard Butrym
  • Patent number: 7397937
    Abstract: A region-growing method for identifying nodules in an anatomical volume segments a 3-D image volume by controlled voxel growth from seed points. The process is based on creation and use of a distance map for tracking the distance of vessel voxels from a predetermined location. A volume map is created that identifies the largest sphere that can pass between a voxel and a predetermined location without touching a non-vessel voxel. The ratio between the distance map and the volume map is analyzed to find regions more likely to contain nodules, the features of which can be extracted or otherwise highlighted.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: July 8, 2008
    Assignee: R2 Technology, Inc.
    Inventors: Alexander C. Schneider, Susan A. Wood
  • Patent number: 7359538
    Abstract: An algorithm is disclosed that detects and analyzes possible lesions that are left in contact with a structural boundary. A morphological closing with a structuring element is performed along the boundary to detect lesions within the threshold of the structuring element. A deformable surface-based analysis is performed on distinctive surfaces of the structure for the identification of lesions. The integrated use of a deformable surface model and chamfer distance potential enables explicit representation of regularized, or smoothed, surfaces from which lesion candidates may be detected.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: April 15, 2008
    Assignee: R2 Technology
    Inventors: Xiaolan Zeng, Wei Zhang
  • Patent number: 7346202
    Abstract: A CAD system pre-analyzes a medical image to automatically determine whether contrast agent was introduced into the patient before forming that image. In one embodiment, contrast agent detection is performed by comparing the voxel values in known blood-containing areas to voxel values of known water-containing areas, and if there is a substantial difference above a preferred threshold, then it is determined that this patient was indeed injected with the contrast agent. Upon finding that the patient was indeed injected with contrast agent, the CAD algorithm then automatically performs both a detection algorithm that uses the contrast agent and one that does not and notifies the clinician that both sets of results are available to look at. However, if it is determined that the patient was not injected with contrast agent, the CAD algorithm does not perform the algorithm that uses the contrast agent does not give the user the option to view any results from such algorithm.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: March 18, 2008
    Assignee: R2 Technology, Inc.
    Inventor: Alexander C. Schneider
  • Patent number: 7336809
    Abstract: A method and system of volume segmentation is disclosed. To address throughput speed and accuracy requirements, the segmentation is divided into two stages: presegmentation and detailed segmentation. In presegmentation, a digital image volume is processed to identify anatomical structures from image backgrounds in a gross manner possibly at reduced image resolution. Detailed segmentation then involves refining and segmenting further the fine details within the anatomical structures identified by presegmentation. One result of the overall volume segmentation algorithm is a volume in which segmented regions of interest, such as nodules, are identified.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: February 26, 2008
    Assignee: R2 Technology, Inc.
    Inventors: Xiaolan Zeng, Wei Zhang, Alexander C. Schneider
  • Patent number: 7298876
    Abstract: A method and apparatus for providing testing a computer aided diagnosis (CAD)-based system comprising receiving radiological image of a patient acquired using at least one piece of radiological equipment at least partially controlled by a technologist, the patient being controlled by the technologies relative to the radiological equipment in acquiring said radiological image.
    Type: Grant
    Filed: November 4, 2002
    Date of Patent: November 20, 2007
    Assignee: R2 Technology, Inc.
    Inventors: Julian Marshall, Keith W. Hartman
  • Patent number: 7286695
    Abstract: An algorithm is quickly scans a digital image volume to detect density nodules. A first stage is based on a transform to quickly highlight regions requiring further processing. The first stage operates with somewhat lower sensitivity than is possible with more detailed analyses, but operates to highlight regions for further analysis and processing. The transform dynamically adapts to various nodule sizes through the use of radial zones. A second stage uses a detailed gradient distribution analysis that only operates on voxels that pass a threshold of the first stage.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: October 23, 2007
    Assignee: R2 Technology, Inc.
    Inventors: Harlan M. Romsdahl, Wei Zhang, Alexander C. Schneider
  • Patent number: 7272250
    Abstract: A region-growing method for identifying nodules in an anatomical volume segments a 3-D image volume by controlled voxel growth from seed points. The process is based on creation and use of a distance map for tracking the distance of vessel voxels from a predetermined location. A volume map is created that identifies the largest sphere that can pass between a voxel and a predetermined location without touching a non-vessel voxel. The ratio between the distance map and the volume map is analyzed to find regions more likely to contain nodules, the features of which can be extracted or otherwise highlighted.
    Type: Grant
    Filed: November 23, 2001
    Date of Patent: September 18, 2007
    Assignee: R2 Technology, Inc.
    Inventors: Alexander C. Schneider, Susan A. Wood
  • Patent number: 7203348
    Abstract: A method and apparatus for correcting for a distortion in a mammogram. The method comprises classifying pixels as either likely fat or likely not-fat. The method further comprises identifying a candidate distortion and calculating a histogram of the likely fat and the likely not-fat pixels at the candidate distortion. The method further comprises evaluating a quality of the candidate distortion based on features of the histograms of pixel values in the fat and dense tissue classes. The distortion may be a two dimensional tilt of the plates or a three dimensional deformation of the plates as in a bend.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: April 10, 2007
    Assignee: R2 Technology, Inc.
    Inventors: Nicolaas Karssemeijer, Alexander Caldwell Schneider
  • Publication number: 20070041623
    Abstract: Managing a patient worklist in a radiology environment is described, the patient worklist identifying a plurality of medical imaging cases to be reviewed at a radiology review workstation. For each case, a set of CAD-computed metrics is received, the CAD-computed metrics being derived from an operation of a CAD processing algorithm on that case. According to a preferred embodiment, the cases in the patient worklist are sorted according to at least one of the CAD-computed metrics. The reviewing radiologist is provided with greater insight into, and control over, patient workflow at the radiology review workstation. Also described is a graphical user interface for easy user customization of the case sorting criteria. Examples of case sorting criteria include a number of CAD markers per case metric, a maximum suspiciousness metric, and an anatomical complexity metric.
    Type: Application
    Filed: August 18, 2005
    Publication date: February 22, 2007
    Applicant: R2 Technology, Inc.
    Inventors: Jimmy Roehrig, Julian Marshall
  • Patent number: 7174515
    Abstract: A method and apparatus for providing an independent display system for a computer aided detection (CAD) system that analyzes medical images. The independent display system comprises a screen to display a medical image including any marked regions of interest and a plurality of icons to interact with the screen. For one embodiment, the screen is a touch screen, such that the independent display system does not require a keyboard or cursor controller.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: February 6, 2007
    Assignee: R2 Technology, Inc.
    Inventors: Julian Marshall, Jimmy Roehrig, Sandra J. Stapleton, John R. Johns, II, Paul J. Fehrenbach
  • Publication number: 20070003119
    Abstract: Display and navigation for multiple computer-aided detection (CAD) detections is described. A medical image is displayed to a viewer, and a request is received to instantiate CAD-assisted viewing. A timewise presentation sequence for the CAD detections is automatically computed according to a predetermined sequencing criterion. For each CAD detection, an expanded presentation window is displayed for its associated location in the medical image, the expanded presentation windows being displayed according to the timewise presentation sequence. Also described is a navigational tool comprising a plot of an operating curve onto which a computed feature associated with the CAD algorithm can be mapped, the operating curve characterizing an application of the CAD algorithm to a reference database of mammographic cases having known diagnoses.
    Type: Application
    Filed: July 1, 2005
    Publication date: January 4, 2007
    Applicant: R2 Technology, Inc.
    Inventors: Jimmy Roehrig, Julian Marshall
  • Patent number: 7146031
    Abstract: A method and system for computer-aided detection of abnormal lesions in digital mammograms is described, wherein digital films are processed using an automated and computerized method of detecting the order and orientation of a set of films. In one embodiment, anatomic features are used to detect the order, orientation and identification of a film series. In another embodiment of the invention, a technologist feeds films into the system in any order and orientation. After processing, the system provides an output on a display device to a radiologist that is in an order and orientation preferred by the radiologist. In yet another embodiment of the invention, films from one case are distinguished from films of another case. In this manner and through the use of a bulk loader, a large number of films can be stacked together and fed into the system at one time.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: December 5, 2006
    Assignee: R2 Technology, Inc.
    Inventors: Keith W. Hartman, Julian Marshall, Alexander C. Schneider, Jimmy R. Roehrig
  • Patent number: 7072498
    Abstract: A method and apparatus for analyzing a medical image obtained from one of a plurality of digital modalities, the method comprising transforming or mapping the initial medical image to create a uniform contrast response and appearance regardless of the original modality of the image.
    Type: Grant
    Filed: February 19, 2002
    Date of Patent: July 4, 2006
    Assignee: R2 Technology, Inc.
    Inventors: Jimmy Roehrig, Sussan Pourjavid, Xiaolan Zhang, Haili Chui, Akira Hasegawa
  • Patent number: D1004111
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: November 7, 2023
    Assignee: R2 Technologies, Inc.
    Inventors: Bryan Jon Weber, Gregory F. Hirth, Noel John Ronsvalle
  • Patent number: D1004112
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: November 7, 2023
    Assignee: R2 Technologies, Inc.
    Inventors: Bryan Jon Weber, Gregory F. Hirth, Noel John Ronsvalle
  • Patent number: D1054572
    Type: Grant
    Filed: September 20, 2023
    Date of Patent: December 17, 2024
    Assignee: R2 Technologies, Inc.
    Inventors: Bryan Jon Weber, Gregory F. Hirth, Noel John Ronsvalle