Abstract: The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.
Type:
Grant
Filed:
December 3, 2019
Date of Patent:
October 19, 2021
Assignee:
Race Oncology Ltd.
Inventors:
William J. Garner, Arnie Franklin, John Rothman
Abstract: The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof. Such methods and compositions are particularly useful for treatment of malignancies.
Type:
Grant
Filed:
January 30, 2020
Date of Patent:
October 5, 2021
Assignee:
RACE ONCOLOGY LTD.
Inventors:
William J. Garner, Amie Franklin, John Rothman
Abstract: The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.
Type:
Grant
Filed:
May 31, 2018
Date of Patent:
February 4, 2020
Assignee:
RACE ONCOLOGY LTD.
Inventors:
William J. Garner, Amie Franklin, John Rothman
Abstract: The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.
Type:
Grant
Filed:
May 14, 2018
Date of Patent:
December 10, 2019
Assignee:
RACE ONCOLOGY LTD.
Inventors:
William J. Garner, Amie Franklin, John Rothman
Abstract: The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.
Type:
Grant
Filed:
July 25, 2014
Date of Patent:
June 12, 2018
Assignee:
RACE ONCOLOGY LTD.
Inventors:
William J. Garner, Amie Franklin, John Rothman
Abstract: The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to bisantrene or derivatives, analogs, or prodrugs thereof.
Type:
Grant
Filed:
July 25, 2014
Date of Patent:
May 22, 2018
Assignee:
RACE ONCOLOGY LTD.
Inventors:
William J. Garner, Amie Franklin, John Rothman