Abstract: A medical sealing device for the sealing of a puncture hole in a vessel wall includes an inner member, which is adapted to be positioned at an interior surface of the vessel wall, and an outer member, which is adapted to be positioned outside the vessel wall, the inner member and the outer member being held together by a retaining member. The sealing device further includes a sealing element, which is adapted to be positioned between the vessel wall and the outer member to improve the sealing performance of the sealing device.

Abstract: The invention provides a closure device (1) for sealing an incision channel leading through a vessel wall and into the vessel. The closure device (1) comprises a haemostatic material (3), which is contained in the distal end of an elongated insertion assembly (2). The insertion assembly (2), which comprises a stationary part (4) and a retractable part (5) being slidably movable with regard to each other, is adapted to be attached to an introducer (7) being in position in the incision channel, so that the insertion assembly (2) can be slid along the introducer (7) until the distal end of the insertion assembly (2) is in contact with the vessel wall, where the haemostatic material (3) is delivered in the incision channel by a retracting movement of the retractable part (5).

Abstract: The invention relates to a torque device for a sensor guide wire having a sensor provided at a distal portion and a male connector provided at the proximal end, which torque device comprises a grip body and a cap adapted to be joined to the grip body, and a number of chuck segments provided on the cap or the grip body, wherein the torque device is a one-way device defining an insertion direction for the sensor guide wire and wherein the chuck segments have free ends which are directed in the insertion direction.

Abstract: A transmitter unit with a detachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The detachable energy source can be a battery pack provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.

Abstract: A sensor and guide wire assembly (21; 41; 61; 81) for intravascular measurements of a physiological variable in a living body includes a sensor element (22; 42; 62; 82) mounted at a distal sensor portion (23; 43; 63; 83) of a guide wire (24; 44; 64; 84), wherein the sensor portion exhibits a maximal cross-sectional dimension which is larger than a maximal cross-sectional dimension of guide wire portions (28, 30; 48, 50; 68, 70) located proximally of the sensor portion.

Abstract: Measurement system comprising a sensor wire provided, at its distal end, with a physiological condition sensor to measure a physiological condition inside a patient, and to provide measured data to an external device, the measurement system comprises a transceiver unit adapted to be connected to the proximal end of the sensor wire, and a communication unit arranged in connection with the external device. The transceiver unit is adapted to communicate, by a communication signal, with the communication unit, in order to transfer measured data to the external device. The communication signal, including the measured data, is generated by the transceiver unit and transferred as an output signal and the communication unit is arranged to be connected to a standard input/output connector of the external device and to communicate with the external device in accordance with an established standard, or in accordance with relevant parts of an established standard, e.g. BP22 or USB.

Abstract: A femoral compression device (1) for compressive bearing against the femoral artery of a patient, comprising a base plate (2), an inflatable air cushion (4), and an electronic manometer (8) connected to the inflatable air cushion for measurement of the current pressure difference between the pressure prevailing inside the inflatable air cushion and the ambient air pressure. The femoral compression device can further comprise a mechanical device (11; 46) which prevents an air opening leading to the inflatable air cushion from being closed before the manometer is zeroed.

Abstract: Sensor and guide wire assembly (1; 21) for intravascular measurement of physical variables inside a living body and comprises a proximal end portion (2; 22) and a sensor element (9; 29), which is located in a distal portion of the sensor and guide wire assembly (1; 21), and is characterized in that a proximal tube (3; 23) is provided, which extends from said proximal portion (2; 22) to a proximal end of a hollow stranded wire (4; 24), which extends to the distal end portion wherein the sensor element (9; 29) is located.

Abstract: The invention relates to a medical sealing device (1) for the sealing of a puncture hole in a vessel wall, and comprises an inner member (2), which is adapted to be positioned at an interior surface of the vessel wall, and an outer member (3), which is adapted to be positioned outside the vessel wall, the inner member (2) and the outer member (3) being held together by a retaining member (4), wherein at least one of said inner member (2), outer member (3) and retaining member (4) is made from at least one shape memory polymer.

Abstract: During use there is a risk that a male connector for a guide wire is bent. With the present male connector (1) more material with high modulus of elasticity can be provided inside the male connector (1), which makes the male connector (1) more bending resistant. The male connector (1) comprises a core wire (3), a plurality of conductive members (4) spaced apart longitudinally along said core wire (3), a plurality of conductors (5) disposed along the core wire (3), each of the conductors (5) being connected to a respective conductive member (4). The connector (1) has such a configuration that the conductors (5) are protected from damage at the location where the conductors (5) connect to the conductive members (4).

Abstract: The invention relates to a method and a system for determining the blood flow in an individual coronary artery of a patient, wherein the method comprises the steps of positioning a temperature sensor mounted at a distal portion of a guide wire at a distal position in the coronary artery, positioning an infusion catheter in the coronary artery such that the distal end of the infusion catheter is proximally of the temperature sensor, measuring the blood temperature with the temperature sensor, infusing cold indicator fluid with a known infusion rate and known or measurable temperature into the coronary artery by the infusion catheter, measuring the temperature of the mixture of blood and indicator fluid by the temperature sensor, and calculating the coronary blood flow by a formula based on the known and measured quantities. In an extended version, the method comprises steps for relating the calculated coronary flow value to related normal flow values, or related FFR values, or a related flow resistance.

Abstract: Pressure measurement system comprising a pressure sensor wire with a pressure sensor to measure pressure inside a patient, and to provide measured pressure data to an external device. The pressure sensor wire is adapted to be connected, at its proximal end, to a transceiver unit that is adapted to wirelessly communicate via a communication signal with a communication unit arranged in connection with an external device, in order to transfer measured pressure data to the external device. The pressure data to be transferred is generated by the transceiver unit and transferred as a data stream. Preferably, the communication signal is a radio frequency signal.

Abstract: A device to seal an incision in a blood vessel includes an inner member and an outer member. A suture connects the inner member and the outer member. A first portion of the suture is embedded within a second portion of the suture such that as tension in the suture increases the first and second portions are held together. According to certain embodiments, the second portion is not part of a first suture portion, and both the first and second portions are used to retain the outer member in place. A method of making such a device is also described.

Abstract: An indicator device for visually indicating a pressure of blood inside a blood vessel includes: a body, the body comprising a duct extending in the body and having a sealed proximal end; a distal end portion adapted to be positioned inside the blood vessel and including a liquid inlet opening in fluid communication with the duct; and a window including an at least semi-transparent section configured to enable visual observation of blood entering into the duct via the inlet opening when the inlet opening is located inside the blood vessel.

Abstract: The present invention relates to a sensor assembly arranged to be disposed in a body for measuring a physiological variable. A basic idea of the present invention is to provide a sensor and guide wire assembly which communicates with an external unit by an inductive coupling between a first coil provided in the sensor assembly and a second, external coil which is disposed in or connected to the external unit. The external unit is preferably the same unit that is used to numerically or graphically display the physiological variables that are measured with the sensor and guide wire assembly. With the terminology introduced above, it should here be clear that both the signal transfer from the sensor as well as the energy feeding from the external unit to the sensor may be accomplished through the inductive coupling between the first and second coils.

Abstract: A femoral compression device (1; 41; 51; 61) for compressing a femoral artery of a patient is provided. The femoral compression device (1; 41; 51; 61) comprises a pressure device (7; 21; 31; 42; 55; 62), a compression member (8; 43; 56; 65) for compressive bearing against a puncture site, a base portion (3; 44; 52) provided with two opposing extensions (4, 5; 45, 46; 53, 54), to the ends of which a belt (6), which is adapted to be arranged around the patient's body, can be fixed. According to the invention, the pressure device (7; 21; 31; 42; 55; 62) is characterized by non-uniform overall action constants, such that when a low compression pressure is applied, the pressure device (7; 21; 31; 42; 55; 62) exhibits a small action constant, and when a high compression pressure is applied, the pressure device (7; 21; 31; 42; 55; 62) exhibits a large action constant.

Abstract: The invention relates to a sensor and guide wire assembly for intravascular measurements within a living body, wherein a sensor element, which is arranged at a distal portion of a guide wire, comprises at least one piezoresistive nanowire.

Abstract: Pressure measurement device (2) including a pressure sensor (6) adapted to perform pressure measurements in the left ventricle of a heart (8). The sensor is connected to a measurement unit (10) to receive pressure measurement values obtained from the sensor, and to a processing means (12) for determining a set of pressure values, said processing means then determines a set of first order time derivative values determined from the set of pressure values.

Abstract: The invention provides an air cushion unit (4) for use in conjunction with a compression device for stopping bleeding from puncture wounds. The air cushion unit (4) comprises a base plate (5), an inflatable air cushion (6), which is attached to the base plate (5), and an internal telescopic guide (7), connecting the base plate (5) with the top of the air cushion (6). Throughout the pressurizing of the inflatable air cushion (6), the length of the telescopic guide (7) corresponds to the degree of expansion of the air cushion (6), thereby providing an internal support for the air cushion unit (4), which eliminates undesired, irregular movements of the air cushion (6).

Abstract: The invention relates to a medical sealing device (1) for the sealing of a puncture hole in a vessel wall, and comprises an inner member (2), which is adapted to be positioned at an interior surface of the vessel wall, and an outer member (3), which is adapted to be positioned outside the vessel wall, the inner member (2) and the outer member (3) being held together by a retaining member (4). The sealing device (1) comprises further a haemostatic agent (5), which can be provided at an inner side of the outer member (3) to improve the sealing performance of the sealing device (1).