Abstract: The invention provides a microfluidic system comprising a cartridge coupled to a motor and adapted to move a fluid sample to a plurality of locations on the cartridge.
Type:
Application
Filed:
October 23, 2020
Publication date:
December 8, 2022
Applicant:
RADISENS DIAGNOSTICS LTD.
Inventors:
Fabio Miguel Rolo Pereria, Donal Cronin, David Doolan, Yan Zhao, Eoin O'Nuallain
Abstract: The invention provides a microfluidic system comprising a cartridge coupled to a motor and adapted to move a fluid sample to a plurality of locations on the cartridge. The cartridge is configured to rotate on an inclined plane, thus providing for a combination of centrifugal force and gravitational force to move the fluid sample within the cartridge. Such a configuration may facilitate the performance of a sequential assay by making it easier to move a fluid radially inwards within the cartridge. The cartridge provided comprises a reaction chamber (15) with at least three zones within the chamber: a first zone (Zone A) is positioned radially outward comprises a cuvette (45) for optical measurement; a second and third zones (Zones B and C) are positioned closer to a centre of rotation (25) and may comprise dried reagents spots (R1, R2).
Type:
Application
Filed:
April 29, 2019
Publication date:
July 29, 2021
Applicant:
RADISENS DIAGNOSTICS LTD.
Inventors:
David Doolan, Donal Cronin, Eoin O'Nuallain, Fabio Miguel Rolo Pereira, Yan Zhao
Abstract: The invention relates to a microfluidic system for processing biological samples comprising a transfer pipette; a platform adapted to provide at least one receiving chamber and configured to receive said transfer pipette, and a distal output chamber wherein a biological sample from the transfer pipette is dispensed into the output chamber when a centrifugal force is applied.
Abstract: The invention relates to a microfluidic system for processing biological samples comprising a transfer pipette; a platform adapted to provide at least one receiving chamber and configured to receive said transfer pipette, and a distal output chamber wherein a biological sample from the transfer pipette is dispensed into the output chamber when a centrifugal force is applied.
Abstract: The invention relates to a microfluidic system for processing biological samples comprising a rotary motor; a means for controlling said motor; a platform coupled to the rotary motor and adapted to provide at least one particle-washing structure and one particle receiving structure for receiving washed particles; and a detection zone for detection of particles of the sample in the particle receiving structure while the platform rotates. The invention provides a sample processing system that is both automated and prone to fewer errors than manual processing. This is accomplished using a centrifugal microfluidic platform that can process raw biological samples (e.g., blood, sputum, urine,) in order to perform high-quality bead-based immunofluorescent assays. The invention uses a simple rotary motor and custom-designed plastic disc to perform the sample preparation steps outlined above.
Type:
Application
Filed:
June 5, 2012
Publication date:
August 28, 2014
Applicant:
RADISENS DIAGNOSTICS LTD.
Inventors:
Greg Kellogg, Jerry O'Brien, Eoin O'Nuallain, Damian Curtin