Patents Assigned to RADIUS PHARMACEUTICALS, INC.
  • Stable cannabinoid formulations
    Patent number: 11911361
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: February 27, 2024
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • Methods for treating cancer
    Patent number: 11857518
    Abstract: Disclosed herein are methods of treating one or more tumors by administering to the subject a therapeutically effective amount of a combination of RAD1901 or solvates (e.g., hydrate) or salts thereof and one or more second therapeutic agent(s) (e.g., everolimus). The cancer is an estrogen-dependent cancer, such as breast cancer, ovarian cancer, colon cancer, endometrial cancer, or prostate cancer.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: January 2, 2024
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventor: Gary Hattersley
  • Methods for treating cancer
    Patent number: 11819480
    Abstract: Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject having a drug-resistant estrogen receptor alpha positive cancer or a mutant estrogen receptor alpha positive cancer. The methods entail administering to the subject a therapeutically effective amount of RAD1901 having the structure: or a salt or solvate thereof.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: November 21, 2023
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventors: Fiona Garner, Gary Hattersley
  • Polymorphic forms of RAD1901-2HCL
    Patent number: 11708318
    Abstract: Various polymorphic forms of RAD1901-2HCl, including three crystalline and amorphous forms, are prepared and characterized. Uses of the various polymorphic forms of RAD1901-2HCl for cancer treatment are also disclosed.
    Type: Grant
    Filed: September 14, 2021
    Date of Patent: July 25, 2023
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventors: Michael Paul Cruskie, Jr., Joshua Kyle Bolger, Jonathan Blake McKenzie, Pratik Sheth, Richard Edwards, Alex Eberlin, Michael Markey
  • Polymorphic forms of RAD1901-2HCl
    Patent number: 11643385
    Abstract: A solid form of RAD1901-2HCl having an X-ray powder diffraction pattern comprising a peak, in terms of 2-theta, at 11.53 degrees 2?±0.2 degrees 2?, and compositions, methods, and processes thereof.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: May 9, 2023
    Assignee: Radius Pharmaceuticals, Inc.
    Inventors: Michael Paul Cruskie, Joshua Kyle Bolger, Jonathan Blake McKenzie, Pratik Sheth, Richard Edwards, Alex Eberlin, Michael Markey
  • STABLE CANNABINOID FORMULATIONS
    Publication number: 20220280446
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Application
    Filed: February 18, 2022
    Publication date: September 8, 2022
    Applicant: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • Methods for treating cancer
    Patent number: 11413258
    Abstract: Disclosed herein are methods of inhibiting tumor growth or producing tumor regression in a subject by administering to the subject a therapeutically effective amount of a combination of palbociclib and RAD1901.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: August 16, 2022
    Assignee: Radius Pharmaceuticals, Inc.
    Inventor: Gary Hattersley
  • Estrogen receptor-modulating compounds
    Patent number: 11384068
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: July 12, 2022
    Assignee: Radius Pharmaceuticals, Inc.
    Inventor: Chris Miller
  • STABLE CANNABINOID FORMULATIONS
    Publication number: 20220184215
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Application
    Filed: December 22, 2021
    Publication date: June 16, 2022
    Applicant: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar VANGARA, Huaguang LI, Ningxin YAN, Hung Q. Nguyen, Venkat R. GOSKONDA
  • Stable cannabinoid formulations
    Patent number: 11331279
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: May 17, 2022
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • STABLE CANNABINOID FORMULATIONS
    Publication number: 20220125932
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Application
    Filed: November 5, 2021
    Publication date: April 28, 2022
    Applicant: RADIUS PHARMACEUTICALS INC.
    Inventors: Kiran Kumar VANGARA, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • STABLE CANNABINOID FORMULATIONS
    Publication number: 20220054450
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Application
    Filed: November 5, 2021
    Publication date: February 24, 2022
    Applicant: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • Stable cannabinoid formulations
    Patent number: 11224660
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: January 18, 2022
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • STABLE CANNABINOID FORMULATIONS
    Publication number: 20210330797
    Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
    Type: Application
    Filed: July 6, 2021
    Publication date: October 28, 2021
    Applicant: RADIUS PHARMACEUTICALS, INC.
    Inventors: Kiran Kumar Vangara, Huaguang Li, Ningxin Yan, Hung Q. Nguyen, Venkat R. Goskonda
  • Polymorphic forms of RAD1901-2HCL
    Patent number: 11148996
    Abstract: Various polymorphic forms of RAD1901-2HCl, including three crystalline and amorphous forms, are prepared and characterized. Uses of the various polymorphic forms of RAD1901-2HCl for cancer treatment are also disclosed.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: October 19, 2021
    Assignee: Radius Pharmaceuticals, Inc.
    Inventors: Michael Paul Cruskie, Jr., Joshua Kyle Bolger, Jonathan Blake McKenzie, Pratik Sheth, Richard Edwards, Alex Eberlin, Michael Markey
  • Polymorphic forms of RAD1901-2HCl
    Patent number: 10745343
    Abstract: Various polymorphic forms of RAD1901-2HCl, including three crystalline and amorphous forms, are prepared and characterized. Uses of the various polymorphic forms of RAD1901-2HCl for cancer treatment are also disclosed.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: August 18, 2020
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventors: Michael Paul Cruskie, Jr., Joshua Kyle Bolger, Jonathan Blake McKenzie, Pratik Sheth, Richard Edwards, Alex Eberlin, Michael Markey
  • Polymorphic forms of RAD1901-2HCL
    Patent number: 10385008
    Abstract: Various polymorphic forms of RAD1901-2HCl, including three crystalline and amorphous forms, are prepared and characterized. Uses of the various polymorphic forms of RAD1901-2HCl for cancer treatment are also disclosed.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: August 20, 2019
    Assignee: Radius Pharmaceuticals, Inc.
    Inventors: Michael Paul Cruskie, Jr., Joshua Kyle Bolger, Jonathan Blake McKenzie, Pratik Sheth, Richard Edwards, Alex Eberlin, Michael Markey
  • Selective androgen receptor modulators
    Patent number: 9920044
    Abstract: This invention provides compounds of formula I, pharmaceutical compositions comprising a compound of formula I and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type 2 diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds and intermediates useful in the preparation of same.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: March 20, 2018
    Assignee: RADIUS PHARMACEUTICALS, INC.
    Inventor: Chris P. Miller