Abstract: Apparatus for driving fluid between first and second anatomical sites of a subject is provided, comprising (1) a first electrode, configured to be coupled to the first anatomical site of the subject; (2) a second electrode, configured to be coupled to the second anatomical site of the subject; and (3) a control unit, configured to (i) detect a pressure difference between the first and second anatomical sites, and (ii) in response to the detected pressure difference, drive fluid between the first and second anatomical sites by applying a treatment voltage between the first and second electrodes. Other embodiments are also described.

Abstract: Apparatus (20) is provided, including a bifurcation stent (50) comprising one or more electrodes (32), the stent (50) configured to be placed in a primary passage (52) and a secondary passage (54) of a blood vessel (30), and a control unit (34), configured to drive the electrodes (32) to apply a signal to a wall (36) of the blood vessel (30), and to configure the signal to increase nitric oxide (NO) secretion by the wall (36). Other embodiments are also described.

Abstract: Apparatus is configured to drive first action potentials orthodromically in a first direction along a nerve of a subject, and second action potentials orthodromically along the nerve in an opposite direction to the first direction. The apparatus includes: (1) first and second excitation units configured to be placed in a proximity of the nerve of the subject; (2) a blocking unit disposed between the excitation units and placeable in a proximity of the nerve of the subject; and (3) a control unit, configured: (i) to drive the first and second excitation units to apply, respectively, first and second excitatory currents to the nerve of the subject, and (ii) to drive the blocking unit to apply a blocking current to the nerve of the subject that blocks action potentials that propagate from the first and second excitatory units toward the blocking unit. Other embodiments are also described.

Abstract: An accommodating intraocular lens implant includes an anterior floating lens unit, a posterior lens unit, an anterior lens link, a posterior lens link, and an anterior rim link, which comprises an anterior rim jointed element. An anterior rim complex is disposed such that the anterior floating lens unit is movable toward and away from the anterior rim complex, in an anterior-posterior direction. A lever is connected (a) at a first longitudinal site along the lever, to the anterior floating lens unit by the anterior lens link, (b) at a second longitudinal site along the lever, to the anterior rim complex by the anterior rim link, and (c) at a third longitudinal site along the lever, to the posterior lens unit by the posterior lens link. The second site is longitudinally between the first and the third sites along the lever, such that the second site serves as a fulcrum for the lever.

Abstract: Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

Abstract: Apparatus for treating a body of a subject is provided. The apparatus includes (1) a first electrode, configured to be placed at a first site in the body of the subject, (2) a second electrode, configured to be placed at a second site in the body of the subject, (3) a pressure sensor, configured to detect a pressure at at least the first site, and (4) a control unit, configured to, at least in part responsively to the detected pressure, induce electroosmotic movement of a fluid between the first and second sites, by driving a current between the first and second electrodes. Other embodiments are also described.

Abstract: Apparatus is provided, which includes at least one ultrasound transducer. The ultrasound transducer is configured to be positioned within a lumen of a subject and to ablate tissue surrounding a wall of the lumen without ablating the wall of the lumen, by focusing ultrasound energy on a focal zone that is outside of the wall of the lumen. A transluminal delivery tool is configured to position the ultrasound transducer in the lumen, and a control unit is configured to drive the ultrasound transducer. Other embodiments are also described.

Abstract: Apparatus and methods are provided for use with a heart of a subject, including a set of one or more electrodes. A control unit paces the heart by driving a first electric current via the electrode set into tissue of the subject, in accordance with a first set of parameters. The control unit stimulates nitric oxide production by a portion of the heart by driving a second electric current via the electrode set into the portion of the heart, in accordance with a second set of parameters. Other embodiments are also described.

Abstract: Apparatus (10) is provided for treating an intervertebral disc (20) of a subject. The apparatus (10) includes a first electrode (30), configured to be inserted into a nucleus pulposus (40) of the disc (20), and a second electrode (32), configured to be placed outside of the nucleus pulposus (40), in a vicinity of the nucleus pulposus (40). A control unit (34) is configured to drive a current between the first and second electrodes (30, 32), and to configure the current to electroosmotically drive fluid between inside and outside the nucleus pulposus (40). Other embodiments are also described.

Abstract: Apparatus is provided for treating obstructive sleep apnea, including an external device (24) configured to be incorporated into a household item which further includes: a breathing sensor (28) configured for placement outside of a body of a subject and to sense activity associated with breathing of the subject and a power supply unit (27) configured to power the external device. A control unit (26) coupled to the breathing sensor is configured to generate a signal (32) in response to the sensed activity associated with breathing. A sublingual implant (34) includes a wireless receiver (40) for receiving the signal, and two or more electrodes (42,44) and circuitry (46) coupled to the electrodes. The circuitry is configured to drive the electrodes to apply current to a tissue of the subject in response to the signal, in a plurality of successive periods of inspiration of the subject, even in the absence of a detection of apnea by the control unit.

Abstract: Apparatus and methods are described including a mechanical support element that is placed inside a first vein of a subject. At least one electrode disposed on the mechanical support element is placed inside the first vein, in a vicinity of a site upstream of a bifurcation with a second vein of the subject. A control unit enhances downstream blood flow from the first vein by driving the at least one electrode to divert blood downstream into the second vein by constricting the first vein at the upstream site, by driving the at least one electrode to apply a current to the vicinity of the site. The mechanical support element prevents the first vein from collapsing by providing mechanical support to the vein. Other embodiments are also described.

Abstract: Apparatus and methods are provided, including a sensor, configured to sense a cardiac cycle of a patient and to generate a signal in response thereto. A pressure mechanism is coupled to a site of an artery of the patient, and, in response to the signal, enhances blood flow of the patient in a downstream direction by compressing the artery. A valve is implanted upstream of the site, and inhibits blood flow in an upstream direction due to operation of the pressure mechanism. Other applications are also described.

Abstract: Apparatus for treating obstructive blood flow disorders, is provided, including (1) an external device, configured for placement outside of a body of a subject and to sense a factor of the subject, and to generate a signal in response to the sensed factor, and (2) an implant, which comprises a wireless receiver for receiving the signal, and an effector element, the implant configured and positioned to alter a blood flow of the subject in response to the signal.

Abstract: Apparatus and methods are described, including at least one tool configured to be placed inside a subject's mouth. A first optically-visible marker is coupled to the tool. A second optically-visible marker is coupled to a structure inside the subject's mouth. A plurality of optical cameras are coupled to the tool, and are placed inside the subject's mouth by the tool being placed inside the subject's mouth. The cameras acquire respective images of the inside of the subject's mouth, in which the second optically-visible marker is identifiable. A plurality of optical cameras that are disposed outside the subject's mouth acquire respective images of the tool, while the tool is inside the subject's mouth, in which images the first optically-visible marker is identifiable. Other embodiments are also described.

Abstract: Apparatus for treating a body of a subject is provided. The apparatus includes (1) a first electrode, configured to be placed at a first site in the body of the subject, (2) a second electrode, configured to be placed at a second site in the body of the subject, (3) a pressure sensor, configured to detect a pressure at at least the first site, and (4) a control unit, configured to, at least in part responsively to the detected pressure, induce electroosmotic movement of a fluid between the first and second sites, by driving a current between the first and second electrodes. Other embodiments are also described.

Abstract: Apparatus is provided that includes a swallowable medical treatment device, which is configured to initially assume a contracted state having a volume of less than 4 cm3. The device includes a gastric anchor, which initially assumes a contracted size, and which is configured to, upon coming in contact with a liquid, expand sufficiently to prevent passage of the anchor through a round opening having a diameter of between 1 cm and 3 cm. The device also includes a duodenal unit, which is configured to pass through the opening, and which is coupled to the gastric anchor such that the duodenal unit is held between 1 cm and 20 cm from the gastric anchor. Other embodiments are also described.

Abstract: A method is provided, including identifying a subject as suffering from pain in a first limb of the subject. In response to the identifying, treatment of the pain in the first limb is facilitated by implanting electrodes in a limb of the subject that is contralateral to the first limb. Other embodiments are also described.

Abstract: Paranasal sinus apparatus is provided, including a hole-forming member configured to form a hole through a bone wall of a paranasal sinus of a subject. An implant is provided, having a proximal end and a distal end, and which is shaped to define a lumen. The implant is couplable to the hole-forming member, and is securable to the wall and extendable through the hole, such that the proximal end is disposed external to the paranasal sinus and the distal end is disposed within the paranasal sinus. The implant includes a biodegradable material. Other applications are also described.

Abstract: Apparatus and methods are described for use with (a) a muscle of a body of a subject and (b) an implanted functional device. An electrode is electrically coupled to the muscle. A compressible housing is compressed due to the movement of the muscle. An energy assembly includes a flywheel and an energy converter. The energy assembly (a) stores energy extracted from the movement of the muscle, by rotating the flywheel, (b) causes the muscle to undergo movement by driving a current into the muscle, via the electrode, using the stored energy, and (c) powers the implanted functional device using the stored energy. A chamber, in fluid communication with the housing, receives, from the compressible housing, fluid that is expelled from the compressible housing due to the compression of the compressible housing. Other applications are also described.

Abstract: An ingestible capsule is provided for delivering medication to a subject. A capsule coating dissolves in a gastrointestinal tract of the subject. An inner core of the capsule has an outer surface associated therewith. The outer surface is disposed within the coating and expands when the coating dissolves. A medication is disposed on the outer surface, and the outer surface is configured such that the medication contacts an intestinal wall of the subject when the outer surface expands. Other embodiments are also provided.