Abstract: The present invention relates to a replicon RNA comprising a nucleotide sequence at least containing the 5? untranslated region, the nucleotide sequence encoding NS3 protein, NS4A protein, NS4B protein, NS5A protein and NS5B protein, and the 3? untranslated region on the genomic RNA of hepatitis C virus of genotype 2a.
November 25, 2003
Date of Patent:
May 3, 2011
Toray Industries Inc., Tokyo Metropolitan Organization for Medical Research, Ralf Bartenschlager
Takaji Wakita, Takanobu Kato, Tomoko Date