Abstract: Polymeric conjugates comprising a polymeric backbone having attached thereto a bone targeting moiety and a therapeutically active agent, wherein the bone targeting moiety is attached to one end of the polymeric backbone via a branching unit such that a molar ratio of the bone targeting moiety to the polymer is at least 2:1, are disclosed. Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed.
Type:
Application
Filed:
May 10, 2012
Publication date:
September 18, 2014
Applicants:
Ramont at Tel-Aviv University Ltd., Universita degli Studi di Padova
Abstract: A coating method is disclosed. The coating method comprises placing a substrate and a biomolecule in a chamber and applying a vapor deposition process within the chamber so as to form a solid deposition of the biomolecule on at least a portion of a surface of the substrate.
Type:
Application
Filed:
August 13, 2008
Publication date:
August 12, 2010
Applicant:
Ramont At Tel Aviv University Ltd.
Inventors:
Ehud Gazit, Lihi Adler-Abramovich, Daniel Aronov, Gil Rosenman