Abstract: A catheter fixation device (10) includes a body (12), a catheter (16) having a proximal portion (18) and a distal portion that passes through an opening (14) in the body (12), and an anti-pull-out lock mechanism comprising an arcuate channel (24) bounded by a pair of arcuate walls (25, 26) extending from a floor of the body (12). A coiled portion (22) of the catheter (16) is constrained to move between the arcuate walls (25, 26) during movement of the proximal portion (18) and the distal portion remains substantially in place.