Patents Assigned to Ramscor, Inc.
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Patent number: 10744202Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: GrantFiled: June 11, 2018Date of Patent: August 18, 2020Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20180289810Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: ApplicationFiled: June 11, 2018Publication date: October 11, 2018Applicant: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20180228898Abstract: This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.Type: ApplicationFiled: March 28, 2018Publication date: August 16, 2018Applicant: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 9993558Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: GrantFiled: August 9, 2013Date of Patent: June 12, 2018Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 9814773Abstract: The present invention provides for injectable pharmaceutical sustained release formulations for delivery of active agents, particularly therapeutic proteins, to the eye. The formulations are biocompatible, biodegradable sustained release formulations comprising low-solubility liquid excipients and relatively small amounts (less than about 10%) of biocompatible, biodegradable polymer such as PLA or PLGA polymers. A unit dose of 5 ?L to 100 ?L of the formulation provides for sustained release of the agent for at least 14 days.Type: GrantFiled: June 11, 2012Date of Patent: November 14, 2017Assignees: Ramscor, Inc., Icon Bioscience, Inc.Inventors: Vernon G. Wong, Louis L. Wood, Carol Wood, Glenn T. Huang
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Patent number: 9737606Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: GrantFiled: February 5, 2016Date of Patent: August 22, 2017Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 9474736Abstract: The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of ?-tocopheryl acetate; ?-tocopheryl acetate and about 0.5% aqueous component; or ?-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.Type: GrantFiled: August 25, 2015Date of Patent: October 25, 2016Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 9289428Abstract: The present embodiments provide for sustained release formulations of antioxidants that are useful in treating afflictions of the eye and tumors.Type: GrantFiled: June 11, 2012Date of Patent: March 22, 2016Assignee: RAMSCOR, INC.Inventors: Vernon G. Wong, Louis L. Wood, Carol Wood
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Patent number: 9144566Abstract: The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of ?-tocopheryl acetate; ?-tocopheryl acetate and about 0.5% aqueous component; or ?-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.Type: GrantFiled: March 18, 2014Date of Patent: September 29, 2015Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 9011915Abstract: This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.Type: GrantFiled: January 14, 2011Date of Patent: April 21, 2015Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20140329785Abstract: The present embodiments provide for sustained release formulations of antioxidants that are useful in treating afflictions of the eye and tumors.Type: ApplicationFiled: June 11, 2012Publication date: November 6, 2014Applicant: RAMSCOR, INC.Inventor: Carol Wood
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Publication number: 20140200268Abstract: The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of ?-tocopheryl acetate; ?-tocopheryl acetate and about 0.5% aqueous component; or ?-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.Type: ApplicationFiled: March 18, 2014Publication date: July 17, 2014Applicant: RAMSCOR, INC.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20140140992Abstract: The present invention provides for injectable pharmaceutical sustained release formulations for delivery of active agents, particularly therapeutic proteins, to the eye. The formulations are biocompatible, biodegradable sustained release formulations comprising low-solubility liquid excipients and relatively small amounts (less than about 10%) of biocompatible, biodegradable polymer such as PLA or PLGA polymers. A unit dose of 5 ?L to 100 ?L of the formulation provides for sustained release of the agent for at least 14 days.Type: ApplicationFiled: June 11, 2012Publication date: May 22, 2014Applicants: ICON BIOSCIENCE, INC., RAMSCOR, INC.Inventors: Vernon G. Wong, Louis L. Wood, Glenn T. Huang
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Patent number: 8722728Abstract: The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of ?-tocopheryl acetate; ?-tocopheryl acetate and about 0.5% aqueous component; or ?-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.Type: GrantFiled: October 9, 2009Date of Patent: May 13, 2014Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20130324481Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: ApplicationFiled: August 9, 2013Publication date: December 5, 2013Applicant: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 8541413Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: GrantFiled: September 24, 2008Date of Patent: September 24, 2013Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20110111006Abstract: This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.Type: ApplicationFiled: January 14, 2011Publication date: May 12, 2011Applicant: RAMSCOR, INC.Inventors: Vernon G. WONG, Louis L. Wood
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Patent number: 7906136Abstract: This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.Type: GrantFiled: September 27, 2005Date of Patent: March 15, 2011Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Publication number: 20100093845Abstract: The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of ?-tocopheryl acetate; ?-tocopheryl acetate and about 0.5% aqueous component; or ?-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient.Type: ApplicationFiled: October 9, 2009Publication date: April 15, 2010Applicant: RAMSCOR, INC.Inventors: Vernon G. WONG, Louis L. Wood