Patents Assigned to Randox Laboratories Limited
  • Patent number: 10775394
    Abstract: Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: September 15, 2020
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Peter Fitzgerald, Ivan McConnell, Philip Lowry
  • Patent number: 10620225
    Abstract: The present invention relates to antibodies for use in detecting polymyxins and tracers; and to a single-capture immunodetection method and kits, each utilising the antibodies of the invention, and disclosed tracers.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: April 14, 2020
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
  • Patent number: 10509046
    Abstract: Components for enabling immunodection of indazole synthetic cannabinoids are described including immunogens, haptens, antibodies, methods and kits.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: December 17, 2019
    Assignee: Randox Laboratories Limited
    Inventors: Ivan McConnell, Peter Fitzgerald, Philip Lowry, Elouard Benchikh
  • Patent number: 10416175
    Abstract: An immunoassay method is described which detects O-desmethyltramadol only. This enables an assay of high sensitivity and specificity avoiding false positive results. The unique antibodies incorporated in the immunoassay method can be combined with antibodies which detect mitragynine to provide an assay which increases the possibility of detecting the commonly found drug combination of O-desmethyltramadol and mitragynine.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: September 17, 2019
    Assignee: Randox Laboratories Limited
    Inventors: Ivan McConnell, Elouard Benchikh, Philip Lowry, Peter Fitzgerald
  • Patent number: 10253006
    Abstract: The current invention describes novel immunogens which are used in the production of novel antibodies with unique binding properties in that they cross-react with a variety of phenylpiperazine derivatives. These antibodies enable methods and kits to detect and/or determine phenylpiperazine derivatives (for example mCPP, TFMPP and MeOPP) in an in vitro sample which are advantageous over currently available analytical methods in terms of cost, ease of use, speed and sensitivity.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: April 9, 2019
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
  • Patent number: 10175258
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 8, 2019
    Assignee: RANDOX LABORATORIES LIMITED
    Inventors: Stephen Peter Fitzgerald, Paul John Innocenzi, Ivan Robert McConnell, Philip Andrew Lowry, Elouard Benchikh
  • Patent number: 10094833
    Abstract: The invention relates to a novel antibody which binds to C-SLPI selected from the group consisting of SEQ ID NOs: 3 and 4.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: October 9, 2018
    Assignee: Randox Laboratories Limited
    Inventors: Clifford Taggart, Sinead Weldon, Chris Scott
  • Patent number: 9952206
    Abstract: The invention relates to the field of drug detection and describes antibody-based components methods and kits for the detection and quantification of alkaloids of the plant kratom. The invention is underpinned by novel antibodies which specifically bind to mitragynine alkaloids found in the kratom plant and their metabolites.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: April 24, 2018
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
  • Patent number: 9945877
    Abstract: Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: April 17, 2018
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Peter Fitzgerald, Ivan McConnell, Philip Lowry
  • Patent number: 9863966
    Abstract: The invention provides novel haptens and immunogens for the preparation of novel monoclonal antibodies, which detect the synthetic opioid meperidine and its active metabolite normeperidine. These antibodies enable methods and kits, which are useful in an immunoassay for therapeutic drug monitoring (TDM) and in extending the window of detection for cases of abuse and drug-facilitated sexual assault (DFSA).
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: January 9, 2018
    Assignee: Randox Laboratories Limited
    Inventors: Ivan McConnell, Elouard Benchikh, Philip Lowry, Peter Fitzgerald
  • Patent number: 9784752
    Abstract: The invention describes antibodies that bind venlafaxine and O-desmethylvenlafaxine. The antibodies are derived from novel haptens and immunogens and are used in methods and kits to detect and quantify venlafaxine and O-desmethylvenlafaxine. The invention also describes novel detecting agents which can be used in the methods and kits of the invention.
    Type: Grant
    Filed: April 11, 2013
    Date of Patent: October 10, 2017
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
  • Patent number: 9720005
    Abstract: An immunoassay method for detecting and determining ‘NBOMe’ family designer drugs is described. Also described are components for use in implementing the method, namely, antibodies, detection agents, solid state devices and kits as well as immunogens used to raise the antibodies.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: August 1, 2017
    Assignee: Randox Laboratories Limited
    Inventors: Ivan Robert McConnell, Elouard Benchikh, Peter Fitzgerald, Andrew Philip Lowry
  • Patent number: 9671415
    Abstract: The current invention provides an improved immunoassay for the detection and determination of pyrrolidinophenone based designer drugs in hair and biological fluids (urine, blood, and oral fluid). The generic immunoassay is underpinned by novel, sub-family-specific antibodies, which display surprising sensitivity. The invention further describes substrates comprising an antibody that is specific to compounds of the pyrrolidinophenone family. Also described are the novel immunogens from which the antibodies are derived and kits incorporating the antibodies of the current invention.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: June 6, 2017
    Assignee: Randox Laboratories Limited
    Inventors: Ivan McConnell, Peter Fitzgerald, Philip Lowry, Elouard Benchikh
  • Patent number: 9612237
    Abstract: The invention provides novel antibodies which specifically bind to the methylphenidate metabolite, ritalinic acid, enabling an immunoassay that can detect methylphenidate in biological samples for an extended period following its ingestion. The invention also describes novel conjugates and kits incorporating the antibodies.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: April 4, 2017
    Assignee: Randox Laboratories Limited
    Inventors: Philip Lowry, Elouard Benchikh, Ivan McConnell, Peter Fitzgerald
  • Patent number: 9587035
    Abstract: The invention relates to the detection and quantification of 1-benzylpiperazine and its metabolites. The invention is underpinned by novel polyclonal antibodies with unique binding properties which enable immunoassay methods and kits for various applications.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: March 7, 2017
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
  • Publication number: 20160266153
    Abstract: Antibodies, immunoassay methods and kits thereof are described for the detection and determination of 3-(aminomethyl)-5-methylhexanoic acid. The novel immunogens from which said antibodies are generated are also described.
    Type: Application
    Filed: March 11, 2016
    Publication date: September 15, 2016
    Applicant: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Peter Fitzgerald, Philip Lowry
  • Patent number: 9441033
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: September 13, 2016
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Patent number: 9434687
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: September 6, 2016
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter FitzGerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Patent number: 9435817
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: September 6, 2016
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Publication number: 20160097784
    Abstract: The present invention relates to antibodies for use in detecting polymyxins and tracers; and to a single-capture immunodetection method and kits, each utilising the antibodies of the invention, and disclosed tracers.
    Type: Application
    Filed: October 1, 2015
    Publication date: April 7, 2016
    Applicant: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald