Patents Assigned to Randox Laboratories Limited
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Patent number: 10775394Abstract: Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described.Type: GrantFiled: March 22, 2018Date of Patent: September 15, 2020Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Peter Fitzgerald, Ivan McConnell, Philip Lowry
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Patent number: 10620225Abstract: The present invention relates to antibodies for use in detecting polymyxins and tracers; and to a single-capture immunodetection method and kits, each utilising the antibodies of the invention, and disclosed tracers.Type: GrantFiled: October 1, 2015Date of Patent: April 14, 2020Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
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Patent number: 10509046Abstract: Components for enabling immunodection of indazole synthetic cannabinoids are described including immunogens, haptens, antibodies, methods and kits.Type: GrantFiled: September 21, 2015Date of Patent: December 17, 2019Assignee: Randox Laboratories LimitedInventors: Ivan McConnell, Peter Fitzgerald, Philip Lowry, Elouard Benchikh
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Patent number: 10416175Abstract: An immunoassay method is described which detects O-desmethyltramadol only. This enables an assay of high sensitivity and specificity avoiding false positive results. The unique antibodies incorporated in the immunoassay method can be combined with antibodies which detect mitragynine to provide an assay which increases the possibility of detecting the commonly found drug combination of O-desmethyltramadol and mitragynine.Type: GrantFiled: December 20, 2016Date of Patent: September 17, 2019Assignee: Randox Laboratories LimitedInventors: Ivan McConnell, Elouard Benchikh, Philip Lowry, Peter Fitzgerald
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Patent number: 10253006Abstract: The current invention describes novel immunogens which are used in the production of novel antibodies with unique binding properties in that they cross-react with a variety of phenylpiperazine derivatives. These antibodies enable methods and kits to detect and/or determine phenylpiperazine derivatives (for example mCPP, TFMPP and MeOPP) in an in vitro sample which are advantageous over currently available analytical methods in terms of cost, ease of use, speed and sensitivity.Type: GrantFiled: April 15, 2016Date of Patent: April 9, 2019Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
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Patent number: 10175258Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: November 7, 2014Date of Patent: January 8, 2019Assignee: RANDOX LABORATORIES LIMITEDInventors: Stephen Peter Fitzgerald, Paul John Innocenzi, Ivan Robert McConnell, Philip Andrew Lowry, Elouard Benchikh
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Patent number: 10094833Abstract: The invention relates to a novel antibody which binds to C-SLPI selected from the group consisting of SEQ ID NOs: 3 and 4.Type: GrantFiled: August 6, 2015Date of Patent: October 9, 2018Assignee: Randox Laboratories LimitedInventors: Clifford Taggart, Sinead Weldon, Chris Scott
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Patent number: 9952206Abstract: The invention relates to the field of drug detection and describes antibody-based components methods and kits for the detection and quantification of alkaloids of the plant kratom. The invention is underpinned by novel antibodies which specifically bind to mitragynine alkaloids found in the kratom plant and their metabolites.Type: GrantFiled: February 19, 2014Date of Patent: April 24, 2018Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
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Patent number: 9945877Abstract: Immunoassay methods and their requisite components for the detection and determination of phenethylamines of the 2C and DO sub-families are described.Type: GrantFiled: August 5, 2014Date of Patent: April 17, 2018Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Peter Fitzgerald, Ivan McConnell, Philip Lowry
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Patent number: 9863966Abstract: The invention provides novel haptens and immunogens for the preparation of novel monoclonal antibodies, which detect the synthetic opioid meperidine and its active metabolite normeperidine. These antibodies enable methods and kits, which are useful in an immunoassay for therapeutic drug monitoring (TDM) and in extending the window of detection for cases of abuse and drug-facilitated sexual assault (DFSA).Type: GrantFiled: October 8, 2013Date of Patent: January 9, 2018Assignee: Randox Laboratories LimitedInventors: Ivan McConnell, Elouard Benchikh, Philip Lowry, Peter Fitzgerald
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Patent number: 9784752Abstract: The invention describes antibodies that bind venlafaxine and O-desmethylvenlafaxine. The antibodies are derived from novel haptens and immunogens and are used in methods and kits to detect and quantify venlafaxine and O-desmethylvenlafaxine. The invention also describes novel detecting agents which can be used in the methods and kits of the invention.Type: GrantFiled: April 11, 2013Date of Patent: October 10, 2017Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
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Patent number: 9720005Abstract: An immunoassay method for detecting and determining ‘NBOMe’ family designer drugs is described. Also described are components for use in implementing the method, namely, antibodies, detection agents, solid state devices and kits as well as immunogens used to raise the antibodies.Type: GrantFiled: May 28, 2015Date of Patent: August 1, 2017Assignee: Randox Laboratories LimitedInventors: Ivan Robert McConnell, Elouard Benchikh, Peter Fitzgerald, Andrew Philip Lowry
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Patent number: 9671415Abstract: The current invention provides an improved immunoassay for the detection and determination of pyrrolidinophenone based designer drugs in hair and biological fluids (urine, blood, and oral fluid). The generic immunoassay is underpinned by novel, sub-family-specific antibodies, which display surprising sensitivity. The invention further describes substrates comprising an antibody that is specific to compounds of the pyrrolidinophenone family. Also described are the novel immunogens from which the antibodies are derived and kits incorporating the antibodies of the current invention.Type: GrantFiled: October 2, 2015Date of Patent: June 6, 2017Assignee: Randox Laboratories LimitedInventors: Ivan McConnell, Peter Fitzgerald, Philip Lowry, Elouard Benchikh
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Patent number: 9612237Abstract: The invention provides novel antibodies which specifically bind to the methylphenidate metabolite, ritalinic acid, enabling an immunoassay that can detect methylphenidate in biological samples for an extended period following its ingestion. The invention also describes novel conjugates and kits incorporating the antibodies.Type: GrantFiled: February 21, 2014Date of Patent: April 4, 2017Assignee: Randox Laboratories LimitedInventors: Philip Lowry, Elouard Benchikh, Ivan McConnell, Peter Fitzgerald
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Patent number: 9587035Abstract: The invention relates to the detection and quantification of 1-benzylpiperazine and its metabolites. The invention is underpinned by novel polyclonal antibodies with unique binding properties which enable immunoassay methods and kits for various applications.Type: GrantFiled: July 1, 2013Date of Patent: March 7, 2017Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald
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Publication number: 20160266153Abstract: Antibodies, immunoassay methods and kits thereof are described for the detection and determination of 3-(aminomethyl)-5-methylhexanoic acid. The novel immunogens from which said antibodies are generated are also described.Type: ApplicationFiled: March 11, 2016Publication date: September 15, 2016Applicant: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Peter Fitzgerald, Philip Lowry
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Patent number: 9441033Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: August 14, 2012Date of Patent: September 13, 2016Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Patent number: 9434687Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: August 14, 2012Date of Patent: September 6, 2016Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter FitzGerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Patent number: 9435817Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: August 14, 2012Date of Patent: September 6, 2016Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Publication number: 20160097784Abstract: The present invention relates to antibodies for use in detecting polymyxins and tracers; and to a single-capture immunodetection method and kits, each utilising the antibodies of the invention, and disclosed tracers.Type: ApplicationFiled: October 1, 2015Publication date: April 7, 2016Applicant: Randox Laboratories LimitedInventors: Elouard Benchikh, Ivan McConnell, Philip Lowry, Peter Fitzgerald