Patents Assigned to Rapafusyn Pharmaceuticals, Inc.
  • Rapafucin derivative compounds and methods of use thereof
    Patent number: 11066416
    Abstract: The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: July 20, 2021
    Assignees: The Johns Hopkins University, Rapafusyn Pharmaceuticals, Inc.
    Inventors: Jun Liu, Sam Hong, Brett R. Ullman, Joseph E. Semple, Kana Yamamoto, Puneet Kumar, Magesh Sadagopan, Jennifer C. Schmitt