Abstract: The bag is formed from two layers of a plastic having properties of mutual superficial adhesion. The layers are laid one on top of the other, and define between themselves at least two chambers each containing a different liquid. To simplify the operations of manufacturing and using the bag, without contaminating the liquids contained in the chambers, the chambers are separated from each other by a separating septum formed by a section of mutual adhesion of the two layers, in which the two layers are in intimate superficial contact. The adherent section is bounded by two lines where the layers are folded to define throttle lines which prevent the liquids from getting from the two chambers into the adherent section. To use the bag, the bag is simply unfolded and pressure is applied to the chambers, in such a way as to cause the layers to come apart in the adherent section and the liquids to mix.
Type:
Grant
Filed:
November 5, 1993
Date of Patent:
June 20, 1995
Assignee:
S.I.F.RA. Societa Italiana Farmaceutici Ravizza S.p.A.
Abstract: A flexible container featuring at least two chambers, each containing a predetermined amount of physiological solution for washing the extracorporeal, blood-side circuit of dialysis equipment; a first chamber being U-shaped, and the second chamber being located axially inwards of the first chamber.
Type:
Grant
Filed:
November 24, 1993
Date of Patent:
January 3, 1995
Assignee:
S.I.F. RA. Societa Italiana Farmaceutical Ravizza S.p.A.
Abstract: New piperazino derivatives of formula ##STR1## in which R is a phenyl radical substituted with at least one sulphonamido group or a substituted nitrogenated heterocyclic ring, and A is CO, CH.sub.2, SO.sub.2, possessing inhibiting activity towards carbonic anhydrase.The new products are prepared from compounds of formula R-A-X in which X is OH, SH, halogen, OR"" or SR"" in which R"" is methyl, ethyl, phenyl, carbomethoxy, carboethoxy, and from a piperazino derivative of formula ##STR2## The R' group can also be introduced on termination of the reaction, by removing and substituting a protective group present at the nitrogen.
Abstract: A process for preparing 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one of the formula: ##STR1## utilizing 2',5-dichloro-2-aminobenzophenone, phthalimidoglycine and hydrazine in a single passage and in a single reaction medium under critical reaction conditions.
Abstract: The application describes a process for preparing 2-phenyl derivatives of benzoxazolyl propionic acid of formula ##STR1## in which X is H, Cl, Br, F, or a linear or branched alkyl or 1 to 6 carbon atoms. The process starts from 3-nitro-4-hydroxyphenyl-.alpha.-methyl-acetonitrile which is hydrolysed in the presence of a strong acid, the 3-nitro-4-hydroxyphenyl-.alpha.-methylacetic acid thus obtained is hydrogenated in the presence of Pd on carbon, and the 3-amino-4-hydroxyphenyl-.alpha.-methylacetic acid deriving therefrom is first reacted with benzoyl chloride or with para-substituted benzoyl chloride in the presence of an alkaline base, and then with 85% phosphoric acid to complete the formation of the oxazolinic ring.