Patents Assigned to RC BIOTECHNOLOGIES, INC.
  • Covalent linkers in antibody-drug conjugates and methods of making and using the same
    Patent number: 10772965
    Abstract: The present invention provides novel and advantageous compositions having a linker capable of covalently coupling one or more free thiols of an antibody. Specifically, provided herein are the molecular structures, synthetic pathways, coupling mechanisms, and applications thereof as used in an antibody-drug conjugate (ADC).
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: September 15, 2020
    Assignee: RC Biotechnologies, Inc.
    Inventors: Changjiang Huang, Jianmin Fang, Hui Ye, Lezhi Zhang
  • Covalent linkers in antibody-drug conjugates and methods of making and using the same
    Patent number: 10537644
    Abstract: The present invention provides novel and advantageous compositions having a linker capable of covalently coupling one or more free thiols of an antibody. Specifically, provided herein are the molecular structures, synthetic pathways, coupling mechanisms, and applications thereof as used in an antibody-drug conjugate (ADC).
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: January 21, 2020
    Assignee: RC BIOTECHNOLOGIES, INC.
    Inventors: Chang Jiang Huang, Jianmin Fang, Hui Ye, Lezhi Zhang