Patents Assigned to REAPPLIX APS
  • Publication number: 20240398300
    Abstract: A blood collection unit is suitable for accelerated blood coagulation of whole blood for subsequent autologous or allogeneic use. The blood collection unit includes an inside surface that has an activation site which accelerates coagulation by having a high roughness. A blood collection unit including an inside surface that has an activation site having a high roughness area, and an interior of the blood collection unit is prepared with a pressure of no more than 255 mBar, and preferably a pressure of no more than 130 mBar.
    Type: Application
    Filed: May 30, 2024
    Publication date: December 5, 2024
    Applicant: REAPPLIX APS
    Inventors: Rasmus LUNDQUIST, Niels Erik HOLM
  • Publication number: 20240269186
    Abstract: A blood product has three consecutive layers that are self-supporting. The first layer of the three consecutive layers has fibrin, the second layer has thrombocytes, and the third layer has leukocytes. The blood product is configured for application to a surgical site that is open so that the third layer is in direct contact with the surgical site.
    Type: Application
    Filed: April 22, 2024
    Publication date: August 15, 2024
    Applicant: Reapplix ApS
    Inventors: Rasmus LUNDQUIST, Niels Erik HOLM
  • Patent number: 12029561
    Abstract: Provided is a blood collection unit suitable for accelerated blood coagulation of whole blood for subsequent autologous or allogeneic use. The blood collection unit includes an inside surface that an activation site accelerating coagulation by having a high roughness. Further provided is a blood collection unit including an inside surface that has an activation site having a high roughness area, and an interior of the blood collection unit has been prepared with a pressure of no more than 255 mBar, and preferably a pressure of no more than 130 mBar.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: July 9, 2024
    Assignee: REAPPLIX APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Patent number: 12011463
    Abstract: A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from whole blood, especially fibrin, thrombocytes and leukocytes. The blood product (10) comprises a first layer (21), a second layer (22) and a third layer (23). The second layer (22) is adjacent to the first layer (21) and the third layer (23). The first layer (21) defines a first outer surface (24) of the blood product (10) and the third layer (23) defining a second outer surface (25) of the blood product (10). The first layer (21) comprises a majority of fibrin, the second layer (22) comprises a majority of thrombocytes and the third layer (23) comprises a majority of leukocytes.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: June 18, 2024
    Assignee: Reapplix ApS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Patent number: 11420138
    Abstract: A container to be used for preparing a multi-layered blood product by centrifugation comprises a substantially cylindrical body (2) with a closed bottom (3) and a top (4) having a filling opening as well as a filter device (15), which is slidable inside the container (1). The filing opening is closed by means of a penetrable membrane (13), and the filter device (15) comprises a substantially planar mesh (16) and a supporting buoyancy body (18). In addition to this, there are means (35, 36, 39, 40, 42), for releasable fixation of the filter device (15) adjacent to the bottom (3) of the container (1).
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: August 23, 2022
    Assignee: Reapplix APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Patent number: 10933095
    Abstract: A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from whole blood, especially fibrin, thrombocytes and leukocytes. The blood product (10) comprises a first layer (21), a second layer (22) and a third layer (23). The second layer (22) is adjacent to the first layer (21) and the third layer (23). The first layer (21) defines a first outer surface (24) of the blood product (10) and the third layer (23) defining a second outer surface (25) of the blood product (10). The first layer (21) comprises a majority of fibrin, the second layer (22) comprises a majority of thrombocytes and the third layer (23) comprises a majority of leukocytes.
    Type: Grant
    Filed: January 19, 2015
    Date of Patent: March 2, 2021
    Assignee: Reapplix APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Publication number: 20200345780
    Abstract: A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from whole blood, especially fibrin, thrombocytes and leukocytes. The blood product (10) comprises a first layer (21), a second layer (22) and a third layer (23). The second layer (22) is adjacent to the first layer (21) and the third layer (23). The first layer (21) defines a first outer surface (24) of the blood product (10) and the third layer (23) defining a second outer surface (25) of the blood product (10). The first layer (21) comprises a majority of fibrin, the second layer (22) comprises a majority of thrombocytes and the third layer (23) comprises a majority of leukocytes.
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Applicant: Reapplix ApS
    Inventors: Rasmus LUNDQUIST, Niels Erik HOLM
  • Patent number: 10716812
    Abstract: A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from whole blood, especially fibrin, thrombocytes and leukocytes. The blood product (10) comprises a first layer (21), a second layer (22) and a third layer (23). The second layer (22) is adjacent to the first layer (21) and the third layer (23). The first layer (21) defines a first outer surface (24) of the blood product (10) and the third layer (23) defining a second outer surface (25) of the blood product (10). The first layer (21) comprises a majority of fibrin, the second layer (22) comprises a majority of thrombocytes and the third layer (23) comprises a majority of leukocytes.
    Type: Grant
    Filed: January 19, 2015
    Date of Patent: July 21, 2020
    Assignee: Reapplix APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Patent number: 10493467
    Abstract: A centrifuge comprising a rotor having a rotational axis, at least one receptacle for a blood sample container, controller means for controlling the rotational speed of the rotor, at least one optical transmitter for transmitting an optical signal, at least one optical receiver for registering the amplitude of the optical signal, where the optical signal is configured to pass through the blood sample container where the optical receiver detects the amplitude of the optical signal when it is directed through the blood sample container, where the amplitude of the optical signal reflects the translucency of the blood sample, where the controller means is configured to discontinue the rotational movement of the rotor when the amplitude of the optical signal over time has fulfilled a predefined pattern indicating that at least the fibrin compression phase of the blood sample is started.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: December 3, 2019
    Assignee: REAPPLIX APS
    Inventors: Rasmus Lundquist, Neils Erik Holm
  • Patent number: 10092864
    Abstract: Container to be used for preparing a multi-layered blood product by centrifugation, said container comprising a substantially cylindrical body (2) with a closed bottom (3) and a top (4) having a filling opening as well as a filter device (15), which is slidable inside the container (1). The filing opening is closed by means of a penetrable membrane (13), and the filter device (15) comprises a substantially planar mesh (16) and a supporting buoyancy body (18). In addition to this, there are means (35, 36, 39, 40, 42), for releasable fixation of the filter device (15) adjacent to the bottom (3) of the container (1).
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: October 9, 2018
    Assignee: REAPPLIX APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Publication number: 20170232452
    Abstract: A centrifuge comprising a rotor having a rotational axis, at least one receptacle for a blood sample container, controller means for controlling the rotational speed of the rotor, at least one optical transmitter for transmitting an optical signal, at least one optical receiver for registering the amplitude of the optical signal, where the optical signal is configured to pass through the blood sample container where the optical receiver detects the amplitude of the optical signal when it is directed through the blood sample container, where the amplitude of the optical signal reflects the translucency of the blood sample, where the controller means is configured to discontinue the rotational movement of the rotor when the amplitude of the optical signal over time has fulfilled a predefined pattern indicating that at least the fibrin compression phase of the blood sample is started.
    Type: Application
    Filed: August 19, 2015
    Publication date: August 17, 2017
    Applicant: REAPPLIX APS
    Inventors: Rasmus LUNDQUIST, Neils Erik HOLM
  • Patent number: 8980301
    Abstract: A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from whole blood, especially fibrin, thrombocytes and leukocytes. The blood product (10) comprises a first layer (21), a second layer (22) and a third layer (23). The second layer (22) is adjacent to the first layer (21) and the third layer (23). The first layer (21) defines a first outer surface (24) of the blood product (10) and the third layer (23) defining a second outer surface (25) of the blood product (10). The first layer (21) comprises a majority of fibrin, the second layer (22) comprises a majority of thrombocytes and the third layer (23) comprises a majority of leukocytes.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: March 17, 2015
    Assignee: Reapplix APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Publication number: 20130140226
    Abstract: Container to be used for preparing a multi-layered blood product by centrifugation, said container comprising a substantially cylindrical body (2) with a closed bottom (3) and a top (4) having a filling opening as well as a filter device (15), which is slidable inside the container (1). The filing opening is closed by means of a penetrable membrane (13), and the filter device (15) comprises a substantially planar mesh (16) and a supporting buoyancy body (18). In addition to this, there are means (35, 36, 39, 40, 42), for releasable fixation of the filter device (15) adjacent to the bottom (3) of the container (1).
    Type: Application
    Filed: September 20, 2011
    Publication date: June 6, 2013
    Applicant: REAPPLIX APS
    Inventors: Rasmus Lundquist, Niels Erik Holm
  • Publication number: 20110135698
    Abstract: A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from whole blood, especially fibrin, thrombocytes and leukocytes. The blood product (10) comprises a first layer (21), a second layer (22) and a third layer (23). The second layer (22) is adjacent to the first layer (21) and the third layer (23). The first layer (21) defines a first outer surface (24) of the blood product (10) and the third layer (23) defining a second outer surface (25) of the blood product (10). The first layer (21) comprises a majority of fibrin, the second layer (22) comprises a majority of thrombocytes and the third layer (23) comprises a majority of leukocytes.
    Type: Application
    Filed: August 24, 2009
    Publication date: June 9, 2011
    Applicant: REAPPLIX APS
    Inventors: Rasmus Lundquist, Niels Erik Holm